Evolution of the concentration of cinnarizine dissolved in the aqueous phase, expressed in percent of the initial dose, during the gastrointestinal lipolysis by rDGL and PPE of Labrasol^® (A) and Gelucire^® 44/14 (B) as a function of time. The vertical line at 30 min represents the end of gastric lipolysis step and the beginning of duodenal lipolysis step. Adapted from (Fernandez et al., 2009).