Open Access
Issue
OCL
Volume 24, Number 2, March–April 2017
Article Number D205
Number of page(s) 4
Section Bioavailability and tissue-targeting dietary lipids: new approaches to their formulation? / Biodisponibilité et ciblage tissulaire des lipides alimentaires : nouvelles stratégies pour la formulation ?
DOI https://doi.org/10.1051/ocl/2016053
Published online 21 February 2017
  • Belayev L, Khoutorova L, Atkins KD, Bazan NG. 2009. Robust docosahexaenoic acid-mediated neuroprotection in a rat model of transient, focal cerebral ischemia. Stroke 40: 3121–3126. [CrossRef] [PubMed] [Google Scholar]
  • Bernoud N, Fenart L, Molière P, et al. 1999. Preferential transfer of 2-docosahexaenoyl-1-lysophosphatidylcholine through an in vitro blood-brain barrier over unesterified docosahexaenoic acid. J Neurochem 72: 338–345. [CrossRef] [PubMed] [Google Scholar]
  • Belkouch M, Hachem M, Elgot A, et al. 2016. The pleiotropic effects of omega-3 docosahexaenoic acid on the hallmarks of Alzheimer's disease. J Nutr Biochem 38: 1–11. [CrossRef] [Google Scholar]
  • Bourre JM, Bonneil M, Clément M, et al. 1993. Function of dietary polyunsaturated fatty acids in the nervous system. Prostaglandins Leukot Essent Fatty Acids 48: 5–15. [CrossRef] [PubMed] [Google Scholar]
  • Bousquet M, Saint-Pierre M, Julien C, Salem N Jr, Cicchetti F, Calon F. 2008. Beneficial effects of dietary omega-3 polyunsaturated fatty acid on toxin-induced neuronal degeneration in an animal model of Parkinson's disease. FASEB J 22: 1213–1225. [CrossRef] [PubMed] [Google Scholar]
  • Brossard N, Croset M, Lecerf J, et al. 1996. Metabolic fate of an oral tracer dose of [13C]docosahexaenoic acid triglycerides in the rat. Am J Physiol 270: R846– R854. [PubMed] [Google Scholar]
  • Brossard N, Croset M, Normand S, et al. 1997. Human plasma albumin transports [13C]docosahexaenoic acid in two lipid forms to blood cells. J Lipid Res 7: 1571–1582. [Google Scholar]
  • Chauveau F, Cho TH, Perez M, et al. 2011. Brain-targeting form of docosahexaenoic acid for experimental stroke treatment: MRI evaluation and anti-oxidant impact. Curr Neurovasc Res 8: 95–102. [CrossRef] [PubMed] [Google Scholar]
  • Croset M, Brossard N, Polette A, Lagarde M. 2000. Characterization of plasma unsaturated lysophosphatidylcholines in human and rat. Biochem J 345(Pt 1): 61–67. [CrossRef] [PubMed] [Google Scholar]
  • Hachem M, Géloën A, Lo Van A, et al. 2016. Efficient docosahexaenoic acid uptake by the brain from a structured phospholipid. Mol Neurobiol 53: 3205–3215. [CrossRef] [PubMed] [Google Scholar]
  • Hashimoto M, Hossain S. 2011. Neuroprotective and ameliorative actions of polyunsaturated fatty acids against neuronal diseases: beneficial effect of docosahexaenoic acid on cognitive decline in Alzheimer's disease. J Pharmacol Sci 116: 150–162. [CrossRef] [Google Scholar]
  • Jensen M, Skarsfeldt T, Hoy C. 1996. Correlation between level of (n-3) polyunsaturated fatty acids in brain phospholipids and learning ability in rats. A multiple generation study. Biochim Biophys Acta 1300: 203–209. [CrossRef] [Google Scholar]
  • Lagarde M, Guichardant M, Picq M, Michaud S, Doutheau S. 2008. Method for preparing acetyl,docosahexaenoyl-glycerophosphocholine and use thereof for delivering polyunsaturated fatty acids. WO 2008/068413. [Google Scholar]
  • Lemaitre-Delaunay D, Pachiaudi C, Laville M, Pousin J, Armstrong M, Lagarde M. 1999. Blood compartmental metabolism of docosahexaenoic acid (DHA) in humans after ingestion of a single dose of [(13)C]DHA in phosphatidylcholine. J Lipid Res 40: 1867–1874. [PubMed] [Google Scholar]
  • Lo Van A, Sakayori N, Hachem M, et al. 2016. Mechanisms of DHA transport to the brain and potential therapy to neurodegenerative diseases. Biochimie 130: 163–167. [CrossRef] [PubMed] [Google Scholar]
  • Makrides M, Neumann M, Gibson R. 1996. Is dietary docosahexaenoic acid essential for term infants? Lipids 31: 115–119. [CrossRef] [PubMed] [Google Scholar]
  • Nguyen LN, Ma D, Shui G, et al. 2014. Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid. Nature 509: 503–506. [CrossRef] [PubMed] [Google Scholar]
  • O'Brien J, Sampson E. 1965. Fatty acid and fatty aldehyde composition of the major brain lipids in normal human gray matter, white matter, and myelin. J Lipid Res 6: 545–551. [PubMed] [Google Scholar]
  • Polette A, Deshayes C, Chantegrel B, Croset M, Armstrong JM, Lagarde M. 1999. Synthesis of acetyl,docosahexaenoyl-glycerophosphocholine and its characterization using nuclear magnetic resonance. Lipids 34: 1333–1337. [CrossRef] [PubMed] [Google Scholar]
  • Quek DBY, Nguyen LN, Fanc H, Silver DL. 2016. Structural insights into the transport mechanism of the human sodium-dependent lysophosphatidylcholine transporter Mfsd2a. J Biol Chem 291: 9383–9394. [CrossRef] [PubMed] [Google Scholar]
  • Rogers L, Valentine C, Keim S. 2013. DHA supplementation: current implications in pregnancy and childhood. Pharmacol Res 70: 13–19. [CrossRef] [Google Scholar]
  • Thies F, Pillon C, Moliere P, Lagarde M, Lecerf J. 1994. Preferential incorporation of sn-2 lysoPC DHA over unesterified DHA in the young rat brain. Am J Physiol 267: R1273–R1279. [PubMed] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.