Open Access
Volume 28, 2021
Article Number 36
Number of page(s) 8
Section Nutrition - Health
Published online 06 July 2021
  • Ayed RB, Rebai A. 2019. Tunisian table olive oil traceability and quality using SNP genotyping and bioinformatics Tools. BioMed Res Int 2019: 1–9, Article ID 8291341. [Google Scholar]
  • Baldoni L, Tosti N, Ricciolini C, et al. 2006. Genetic structure of wild and cultivated olives in the central Mediterranean basin. Ann Bot 98: 935–942. [Google Scholar]
  • Balogun KA, Cheema SK. 2016. Dietary omega-3 polyunsaturated fatty acids reduced adipocyte hypertrophy by downregulating acyl-CoA:diacylglycerol acyltransferase-2 and fatty acids binding protein-4 in a sex dependent fashion. Lipids 51(1): 25–38. [Google Scholar]
  • Barbaro BG, Toietta G, Maggio R, et al. 2014. Effects of the olive-derived polyphenol oleuropein on human health. Int J Mol Sci 15(10): 18508–18524. [Google Scholar]
  • Beiting DP, Hidano S, Baggs JE, et al. 2015. The orphan nuclear receptor TLX is an enhancer of STAT1 – Mediated transcription and immunity to Toxoplasma gondii. PLoS Biol 13(7): e1002200. [Google Scholar]
  • Bento-Abreu A, Tabernero A, Medina JM. 2007. Peroxisome proliferator-activated receptor-alpha is required for the neurotrophic effect of oleic acid in neurons. J Neurochem 103: 871–881. [Google Scholar]
  • Brunelleschi S, Bardelli C, Amoruso A, et al. 2007. Minor polar compounds extra-virgin olive oil extract (MPC-OOE) inhibits NF-kappa B translocation in human monocyte/macrophages. Pharmacol Res 56: 542–549. [Google Scholar]
  • Bulotta S, Celano M, Lepore SM, Montalcini T, Puija A, Russo D. 2014. Beneficial effects of the olive oil phenolics components oleuropein and hydroxytyrosol: Focus on protection against cardiovascular and metabolic diseases. J Transl Med 219: 2–9. [Google Scholar]
  • Busconi M, Foroni C, Corradi M, Bongiorni C, Cattapan F, Fogher C. 2003. DNA extraction from olive oil and its use in the identification of the production cultivar. Food Chem 83: 127–134. [Google Scholar]
  • Cheema SK, Tappia PS, Dhalla NS. 2019. Modification of gene expression in rat cardiomyocytes by linoleic and docosahexaenoic acids. Can J Phys Pharmacol 97(4): 320–327. [Google Scholar]
  • Choi S-G, Won S-R, Rhee H-I. 2010. Oleic acid and inhibition of glucosyltransferase. In: Preedy VR, Watson RR, eds. Olives and olive oil in health and disease prevention. Elsevier Inc., pp. 1375–1383. [Google Scholar]
  • Cicerale S, Lucas LJ, Keast RS. 2012. Antimicrobial, antioxidant and anti-inflammatory phenolic activities in extra virgin olive oil. Curr Opin Biotechnol 23(2): 129–135. [Google Scholar]
  • Clarke DJB, Kuleshov MV, Schilder BM, et al. 2018. eXpression2Kinases (X2K) Web: linking expression signatures to upstream cell signaling networks. Nucl Acids Res 46(W1): 171–179. [Google Scholar]
  • Cocchi M, Tonello L, Martínez ÁJ, Lercker G, Caramia GM. 2009. Extra virgin olive oil and oleic acid. Nutr Clín Diet Hosp 29(3): 12–24. [Google Scholar]
  • Covàs MI, Miró-Casas E, Fitó M, et al. 2003. Bioavailability of tyrosol, an antioxidant phenolic compound present in wine and olive oil, in humans. Drugs Exp Clin Res 29: 203–206. [Google Scholar]
  • Cruz F, Julca I, Gómez-Garrido J, et al. 2016. Genome sequence of the olive tree, Olea europaea. GigaScience 5: 29. [Google Scholar]
  • De la Puerta R, Ruiz-Gutierrez V, Hoult JRS. 1999. Inhibition of leukocyte 5-lipoxygenase by phenolics from virgin olive oil. Biochem Pharmacol 57: 445–449. [Google Scholar]
  • De la Puerta C, Carrascosa-Salmoral MP, Garcia-Luna PP, et al. 2007. Melatonin is a phytochemical in olive oil. Food Chem 104: 609–612. [Google Scholar]
  • Diana A, Michielin O, Zoete V. 2017. SwissADME: A free web tool to evaluate pharmacokinetics, druglikeness and medicinal chemistry friendliness of small molecules. Sci Rep 7: 42717. [Google Scholar]
  • Diana A, Michielin O, Zoete V. 2019. SwissTargetPrediction: Updated data and new features for efficient prediction of protein targets of small molecules. Nucl Acids Res 1–8. [Google Scholar]
  • Dubuquoy L, Rousseaux C, Thuru X, et al. 2006. PPARgamma as a new therapeutic target in inflammatory bowel diseases. Gut 55: 1341–1349. [Google Scholar]
  • Esteves A, Knoll-Gellida A, Canclini L, Silvarrey MC, André M, Babin PJ. 2016. Fatty acid binding proteins have the potential to channel dietary fatty acids into enterocyte nuclei. J Lipid Res 57: 219–232. [Google Scholar]
  • Estruch R, Martinez-Gonzalez MA, Corella D, et al. 2006. Effects of a Mediterranean-style diet on cardiovascular risk factors: A randomized trial. Ann Intern Med 145(1): 1–11. [Google Scholar]
  • Estruch R, Ros E, Salas-Salvadó J, et al. 2018. Primary prevention of cardiovascular disease with a mediterranean diet supplemented with extra-virgin olive oil or nuts. N Engl J Med 378(25): e34. [Google Scholar]
  • Fatoki TH, Ibraheem O, Adeseko CJ, et al. 2021. Melanogenesis, its regulatory process, and insights on biomedical, biotechnological, and pharmacological potentials of melanin as antiviral biochemical. Biointerf Res Appl Chem 11(4): 11969–11984. [Google Scholar]
  • Feltham BA, Balogun KA, Cheema SK. 2019. Omega-3 polyunsaturated fatty acids have an age and sex specific effect to regulate stearoyl-CoA desaturase-1 and myelin basi protein in the cerebellum of C57BL/6 mice. Pros Leuk Essent Fatty Acids 148: 16–24. [Google Scholar]
  • Fernández-Montesinos R, De la Puerta C, García-Luna PP, Reiter RJ, Pozo D. 2010. The occurrence of the biogenic amine melatonin in olive oil: Implications in health and disease prevention. In: Preedy VR, Watson RR, eds. Olives and olive oil in health and disease prevention. Elsevier Inc., pp. 275–282. [Google Scholar]
  • Fernández-Navarro M, Peragón J, Esteban FJ, Amores V, de la Higuera M, Lupiáñez JA. 2010. Maslinic acid: A component of olive oil on growth and protein-turnover rates. In: Preedy VR, Watson RR, eds. Olives and olive oil in health and disease prevention. Elsevier Inc., pp. 1415–1421. [Google Scholar]
  • Fogher C, Busconi M, Sebastiani L, Bracci T. 2010. Olive genomics. In: Olives and olive oil in health and disease prevention. Elsevier Inc., pp. 17–24. [Google Scholar]
  • Gerber M, Hoffman R. 2015. The Mediterranean diet: Health, science and society. Br J Nutr 113(Suppl 2): S4–10. [Google Scholar]
  • Giovannini L, Migliori M, Filippi C, et al. 2002. Inhibitory activity of the white wine compounds, tyrosol and caffeic acid, on lipopolysaccharide-induced tumor necrosis factor-alpha release in human peripheral blood mononuclear cells. Int J Tissue React 24: 53–56. [Google Scholar]
  • Gnoni GV, Natali F, Geelen MJH, Siculella L. 2010. Oleic acid as an inhibitor of fatty acid and cholesterol synthesis. In: Preedy VR, Watson RR, eds. Olives and olive oil in health and disease prevention. Elsevier Inc., pp. 1365–1373. [Google Scholar]
  • Huang TH, Peng G, Kota BP, et al. 2005. Pomegranate flower improves cardiac lipid metabolism in a diabetic rat model: role of lowering circulating lipids. Br J Pharmacol 145: 767–774. [Google Scholar]
  • Iaria DL, Chiappetta A, Muzzalupo I. 2016. A de novo transcriptomic approach to identify flavonoids and anthocyanins “switch-off” in olive (Olea europaea L.) drupes at different stages of maturation. Front Plant Sci 6: 1246. [Google Scholar]
  • Kandel P, Semerci F, Bajic A, et al. 2020. Oleic acid triggers hippocampal neurogenesis by binding to TLX/NR2E1. bioRxiv preprint 1–18. [Google Scholar]
  • Kersten S, Desvergne B, Wahli W. 2000. Roles of PPARs in health and disease. Nature 405: 421–424. [Google Scholar]
  • Khalatbary AR. 2013. Olive oil phenols and neuroprotection. Nutr Neurosci 16(6): 243–249. [Google Scholar]
  • Kliewer SA, Sundseth SS, Jones SA, et al. 1997. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptor alpha and gamma. Proc Natl Acad Sci USA 94: 4318–4323. [Google Scholar]
  • Krey G, Braissant O, L’Horset F, et al. 1997. Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol Endocrinol 11: 779–791. [Google Scholar]
  • Lemay DG, Hwang DH. 2006. Genome-wide identification of peroxisome proliferator response elements using integrated computational genomics. J Lipid Res 47: 1583–7. [Google Scholar]
  • Liu J, Rajendram R, Zhang L. 2010. Effects of oleanolic acid and maslinic acid on glucose and lipid metabolism: Implications for the beneficial effects of olive oil on health. In: Preedy VR, Watson RR, eds. Olives and olive oil in health and disease prevention. Elsevier Inc., pp. 1423–1429. [Google Scholar]
  • Martinez-Gonzalez MA, Salas-Salvado J, Estruch R, et al. 2015. Benefits of the Mediterranean diet: insights from the PREDIMED Study. Progr Cardiovasc Diseases 58: 50–60. [Google Scholar]
  • Miró-Casas E, Farré-Albaladejo M, Covàs MI, et al. 2001. Capillary gas chromatography-mass spectrometry quantitative determination of hydroxytyrosol and tyrosol in human urine after olive oil intake. Anal Biochem 294: 63–72. [Google Scholar]
  • Morales JC, Lucas R. 2010. Structure–activity relationship of phenolic antioxidants and olive components. In: Preedy VR, Watson RR, eds. Olives and olive oil in health and disease prevention. Elsevier Inc., pp. 905–914. [Google Scholar]
  • Moreno JJ. 2003. Effect of olive oil minor components on oxidative stress and arachidonic acid mobilization and metabolism by macrophages RAW 264.7. Free Radic Biol Med 35: 1073–1081. [Google Scholar]
  • Muller M, Kersten S. 2003. Nutrigenomics: Goals and strategies. Nat Rev Genet 4: 315–322. [Google Scholar]
  • Ordovas JM, Mooser V. 2004. Nutrigenomics and nutrigenetics. Curr Opin Lipidol 15: 101–108. [Google Scholar]
  • Pedret A, Catalán Ú, Fernández-Castillejo S, et al. 2015. Impact of virgin olive oil and phenol-enriched virgin olive oils on the HDL proteome in hypercholesterolemic subjects: A double blind, randomized, controlled, cross-over clinical trial (VOHF Study). PLoS ONE 10(6): e0129160. [Google Scholar]
  • Perez-Camino MC, Cert A. 1999. Quantitative determination of hydroxyl pentacyclic triterpene acids in vegetable oils. J Agric Food Chem 47: 1558–1562. [Google Scholar]
  • Perez-Jimenez F. 2005. International conference on the healthy effect of virgin olive oil. Eur J Clin Invest 35: 421–424. [Google Scholar]
  • Rigacci S, Stefani M. 2016. Nutraceutical properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans. Int J Mol Sci 17(6): 843. [Google Scholar]
  • Rodriguez-Morato J, Xicota L, Fito M, et al. 2015. Potential role of olive oil phenolic compounds in the prevention of neurodegenerative diseases. Molecules 20(3): 4655–4680. [Google Scholar]
  • Salas-Salvado J, Bulló M, Babio N, et al. 2011. Reduction in the incidence of type 2 diabetes with the Mediterranean diet: results of the PREDIMED-Reus nutrition intervention randomized trial. Diabetes Care 34(1): 14–19. [Google Scholar]
  • Salas-Salvado J, Bullo N, Estruch R, et al. 2014. Prevention of diabetes with Mediterranean diets: A subgroup analysis of a randomized trial. Ann Intern Med 160(1): 1–10. [Google Scholar]
  • Segura-Carretero A, Menéndez-Menéndez J, Fernández-Gutiérrez A. 2010. Polyphenols in olive oil: the importance of phenolic compounds in the chemical composition of olive oil. In: Preedy VR, Watson RR, eds. Olives and olive oil in health and disease prevention. Elsevier Inc., pp. 167–175. [Google Scholar]
  • Tresserra-Rimbau A, Lamuela-Raventos RM. 2017. Olives and olive oil: A Mediterranean source of polyphenols. In: Kiritsakis A, Shahidi F, eds. Olives and olive oil as functional foods: Bioactivity, chemistry and processing, 1st ed. John Wiley & Sons Ltd, pp. 417–428. [Google Scholar]
  • Unver T, Wu Z, Sterck L, et al. 2017. Genome of wild olive and the evolution of oil biosynthesis. PNAS E9413–E9422. [Google Scholar]
  • Vasto S, Barera A, Rizzo C, et al. 2014. Mediterranean diet and longevity: An example of nutraceuticals? Curr Vasc Pharmacol 12(5): 735–738. [Google Scholar]
  • Wang T, Xiong J-Q. 2016. The orphan nuclear receptor TLX/NR2E1 in neural stem cells and diseases. Neurosci Bull 32(1): 108–114. [Google Scholar]
  • Xu HE, Lambert MH, Montana VG, et al. 1999. Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol Cell 3: 397–403. [Google Scholar]
  • Zhang X, Yang P, Luo X, et al. 2019. High olive oil diets enhance cervical tumour growth in mice: transcriptome analysis for potential candidate genes and pathways. Lipids in Health and Disease 18: 76. [Google Scholar]

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