Issue
OCL
Volume 27, 2020
Lipids and health / Lipides et santé
Article Number 5
Number of page(s) 11
DOI https://doi.org/10.1051/ocl/2020001
Published online 28 January 2020
  • Ahmad A, Moriguchi T, Salem N. 2002. Decrease in neuron size in docosahexaenoic acid-deficient brain. Pediatr Neurol 26(3): 210–218. [Google Scholar]
  • Ailhaud G, et al. 2006. Temporal changes in dietary fats: role of n-6 polyunsaturated fatty acids in excessive adipose tissue development and relationship to obesity. Prog Lipid Res 45(3): 203–236. [CrossRef] [PubMed] [Google Scholar]
  • Amate L, Gil A, Ramirez M. 2001. Feeding infant piglets formula with long-chain polyunsaturated fatty acids as triacylglycerols or phospholipids influences the distribution of these fatty acids in plasma lipoprotein fractions. J Nutr 131(4): 1250–1255. [CrossRef] [PubMed] [Google Scholar]
  • Anderson GJ, et al. 2005. Can prenatal N-3 fatty acid deficiency be completely reversed after birth? Effects on retinal and brain biochemistry and visual function in rhesus monkeys. Pediatr Res 58(5): 865–872. [CrossRef] [PubMed] [Google Scholar]
  • Anderson JW, Johnstone BM, Remley DT. 1999. Breast-feeding and cognitive development: a meta-analysis. Am J Clin Nutr 70(4): 525–535. [CrossRef] [PubMed] [Google Scholar]
  • Armand M, et al. 1996. Effect of human milk or formula on gastric function and fat digestion in the premature infant. Pediatr Res 40(3): 429–437. [CrossRef] [PubMed] [Google Scholar]
  • Armand M, et al. 1999. Digestion and absorption of 2 fat emulsions with different droplet sizes in the human digestive tract. Am J Clin Nutr 70(6): 1096–1106. [CrossRef] [PubMed] [Google Scholar]
  • Bakker EC, et al. 2003. Long-chain polyunsaturated fatty acids at birth and cognitive function at 7 years of age. Eur J Clin Nutr 57(1): 89–95. [CrossRef] [PubMed] [Google Scholar]
  • Bakker EC, et al. 2009. Relationship between long-chain polyunsaturated fatty acids at birth and motor function at 7 years of age. Eur J Clin Nutr 63(4): 499–504. [CrossRef] [PubMed] [Google Scholar]
  • Ballard O, Morrow AL. 2013. Human milk composition: nutrients and bioactive factors. Pediatr Clin North Am 60(1): 49–74. [CrossRef] [PubMed] [Google Scholar]
  • Baumgartner S, et al. 2017. Infant milk fat droplet size and coating affect postprandial responses in healthy adult men: a proof-of-concept study. Eur J Clin Nutr. [CrossRef] [PubMed] [Google Scholar]
  • Baylink DJ, Finkelman RD, Mohan S. 1993. Growth factors to stimulate bone formation. J Bone Miner Res 8(Suppl. 2): S565–S572. [Google Scholar]
  • Bazinet RP, Laye S. 2014. Polyunsaturated fatty acids and their metabolites in brain function and disease. Nat Rev Neurosci 15(12): 771–785. [CrossRef] [PubMed] [Google Scholar]
  • Belfort MB, et al. 2013. Infant feeding and childhood cognition at ages 3 and 7 years: effects of breastfeeding duration and exclusivity. JAMA Pediatr 167(9): 836–844. [CrossRef] [PubMed] [Google Scholar]
  • Benatti P, et al. 2004. Polyunsaturated fatty acids: biochemical, nutritional and epigenetic properties. J Am Coll Nutr 23(4): 281–302. [CrossRef] [PubMed] [Google Scholar]
  • Bernard JY, et al. 2015. The association between linoleic acid levels in colostrum and child cognition at 2 and 3 years in the EDEN cohort. Pediatr Res 77(6): 829–835. [CrossRef] [PubMed] [Google Scholar]
  • Bernard JY, et al. 2017. Breastfeeding, polyunsaturated fatty acid levels in colostrum and child intelligence quotient at age 5–6 years. J Pediatr 183: 43.e3–50.e3. [Google Scholar]
  • Bezelgues JB, et al. 2009. Short communication: milk fat globule membrane as a potential delivery system for liposoluble nutrients. J Dairy Sci 92(6): 2524–2528. [Google Scholar]
  • Bjorkhem I, Meaney S. 2004. Brain cholesterol: long secret life behind a barrier. Arterioscler Thromb Vasc Biol 24(5): 806–815. [CrossRef] [PubMed] [Google Scholar]
  • Boleman SL, et al. 1998. Pigs fed cholesterol neonatally have increased cerebrum cholesterol as young adults. J Nutr 128(12): 2498–2504. [CrossRef] [PubMed] [Google Scholar]
  • Bonnet N, Ferrari SL. 2011. Effects of long-term supplementation with omega-3 fatty acids on longitudinal changes in bone mass and microstructure in mice. J Nutr Biochem 22(7): 665–672. [CrossRef] [PubMed] [Google Scholar]
  • Bonnet N, Ferrari S. 2015 A long-term diet enriched in omega-3 fatty acids improves cortical bone structure and mechanical properties in mice. Bone 44: S414. [Google Scholar]
  • Boucher O, et al. 2011. Neurophysiologic and neurobehavioral evidence of beneficial effects of prenatal omega-3 fatty acid intake on memory function at school age. Am J Clin Nutr 93(5): 1025–1037. [CrossRef] [PubMed] [Google Scholar]
  • Bourlieu C, et al. 2015. The structure of infant formulas impacts their lipolysis, proteolysis and disintegration during in vitro gastric digestion. Food Chem 182: 224–235. [Google Scholar]
  • Breij LM, et al. 2017. Appetite-regulating hormones in early life and relationships with type of feeding and body composition in healthy term infants. Eur J Nutr 56(4): 1725–1732. [CrossRef] [PubMed] [Google Scholar]
  • Brenna JT, Carlson SE. 2014. Docosahexaenoic acid and human brain development: evidence that a dietary supply is needed for optimal development. J Hum Evol 77: 99–106. [CrossRef] [PubMed] [Google Scholar]
  • Brenna JT, et al. 2009. Alpha-linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans. Prostagland Leukot Essent Fatty Acids 80(2-3): 85–91. [CrossRef] [PubMed] [Google Scholar]
  • Brink LR, Gueniot JP, Lonnerdal B. 2019. Effects of milk fat globule membrane and its various components on neurologic development in a postnatal growth restriction rat model. J Nutr Biochem 69: 163–171. [CrossRef] [PubMed] [Google Scholar]
  • Britton JR, Britton HL, Gronwaldt V. 2006. Breastfeeding, sensitivity, and attachment. Pediatrics 118(5): e1436–e1443. [CrossRef] [PubMed] [Google Scholar]
  • Burdge GC, Wootton SA. 2002. Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. Br J Nutr 88(4): 411–420. [CrossRef] [PubMed] [Google Scholar]
  • Campolongo P, et al. 2009. Fat-induced satiety factor oleoylethanolamide enhances memory consolidation. Proc Natl Acad Sci U S A 106(19): 8027–8031. [CrossRef] [PubMed] [Google Scholar]
  • Cao D, et al. 2009. Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function. J Neurochem 111(2): 510–521. [CrossRef] [PubMed] [Google Scholar]
  • Carnielli VP, et al. 1998. Intestinal absorption of long-chain polyunsaturated fatty acids in preterm infants fed breast milk or formula. Am J Clin Nutr 67(1): 97–103. [CrossRef] [PubMed] [Google Scholar]
  • Carrie I, et al. 2000. Specific phospholipid fatty acid composition of brain regions in mice. Effects of n-3 polyunsaturated fatty acid deficiency and phospholipid supplementation. J Lipid Res 41(3): 465–472. [PubMed] [Google Scholar]
  • Carrie I, et al. 2002. Docosahexaenoic acid-rich phospholipid supplementation: effect on behavior, learning ability, and retinal function in control and n-3 polyunsaturated fatty acid deficient old mice. Nutr Neurosci 5(1): 43–52. [CrossRef] [PubMed] [Google Scholar]
  • Carver JD, et al. 2001. The relationship between age and the fatty acid composition of cerebral cortex and erythrocytes in human subjects. Brain Res Bull 56(2): 79–85. [CrossRef] [PubMed] [Google Scholar]
  • Cato A, Hershey T. 2016. Cognition and type 1 diabetes in children and adolescents. Diabetes Spectr 29(4): 197–202. [CrossRef] [PubMed] [Google Scholar]
  • Chalon S. 2006. Omega-3 fatty acids and monoamine neurotransmission. Prostagland Leukot Essent Fatty Acids 75(4-5): 259–269. [CrossRef] [PubMed] [Google Scholar]
  • Chen CT, et al. 2015. Plasma non-esterified docosahexaenoic acid is the major pool supplying the brain. Sci Rep 5: 15791. [CrossRef] [PubMed] [Google Scholar]
  • Clouard C, et al. 2015. Dietary linoleic and alpha-linolenic acids affect anxiety-related responses and exploratory activity in growing pigs. J Nutr 145(2): 358–364. [CrossRef] [PubMed] [Google Scholar]
  • Conklin SM, et al. 2010. Age-related changes of n-3 and n-6 polyunsaturated fatty acids in the anterior cingulate cortex of individuals with major depressive disorder. Prostagland Leukot Essent Fatty Acids 82(2-3): 111–119. [CrossRef] [Google Scholar]
  • Contarini G, Povolo M. 2013. Phospholipids in milk fat: composition, biological and technological significance, and analytical strategies. Int J Mol Sci 14(2): 2808–2831. [Google Scholar]
  • Decsi T, Koletzko B. 1995. Growth, fatty acid composition of plasma lipid classes, and plasma retinol and alpha-tocopherol concentrations in full-term infants fed formula enriched with omega-6 and omega-3 long-chain polyunsaturated fatty acids. Acta Paediatr 84(7): 725–732. [CrossRef] [PubMed] [Google Scholar]
  • Delgado-Noguera MF, Calvache JA, Bonfill Cosp X. 2010. Supplementation with long chain polyunsaturated fatty acids (LCPUFA) to breastfeeding mothers for improving child growth and development. Cochrane Database Syst Rev (12): Cd007901. [Google Scholar]
  • Delplanque B, et al. 2013. A dairy fat matrix providing alpha-linolenic acid (ALA) is better than a vegetable fat mixture to increase brain DHA accretion in young rats. Prostagland Leukot Essent Fatty Acids 88(1): 115–120. [CrossRef] [PubMed] [Google Scholar]
  • Demar JC Jr, et al. 2005. Alpha-linolenic acid does not contribute appreciably to docosahexaenoic acid within brain phospholipids of adult rats fed a diet enriched in docosahexaenoic acid. J Neurochem 94(4): 1063–1076. [CrossRef] [PubMed] [Google Scholar]
  • Deoni SC, et al. 2013. Breastfeeding and early white matter development: a cross-sectional study. Neuroimage 82: 77–86. [CrossRef] [PubMed] [Google Scholar]
  • Deoni S, et al. 2018. Early nutrition influences developmental myelination and cognition in infants and young children. Neuroimage 178: 649–659. [CrossRef] [PubMed] [Google Scholar]
  • DiSantis KI, et al. 2011. Do infants fed directly from the breast have improved appetite regulation and slower growth during early childhood compared with infants fed from a bottle ? Int J Behav Nutr Phys Act 8: 89–89. [CrossRef] [PubMed] [Google Scholar]
  • Duncan RE, Bazinet RP. 2010. Brain arachidonic acid uptake and turnover: implications for signaling and bipolar disorder. Curr Opin Clin Nutr Metab Care 13(2): 130–138. [CrossRef] [PubMed] [Google Scholar]
  • Dyall SC. 2015. Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA. Front Aging Neurosci 7: 52. [CrossRef] [PubMed] [Google Scholar]
  • Efsa panel on dietetic products, N. and allergies. 2014. Scientific opinion on the essential composition of infant and follow-on formulae. EFSA J 12(7): 3760-n/a. [PubMed] [Google Scholar]
  • Escolano-Margarit MV, et al. 2011. Prenatal DHA status and neurological outcome in children at age 5.5 years are positively associated. J Nutr 141(6): 1216–1223. [CrossRef] [PubMed] [Google Scholar]
  • Farquharson J, et al. 1992. Infant cerebral cortex phospholipid fatty-acid composition and diet. Lancet 340(8823): 810–813. [CrossRef] [PubMed] [Google Scholar]
  • Farr OM, Tsoukas MA, Mantzoros CS. 2015. Leptin and the brain: influences on brain development, cognitive functioning and psychiatric disorders. Metabolism 64(1): 114–130. [CrossRef] [PubMed] [Google Scholar]
  • Field CJ. 2005. The immunological components of human milk and their effect on immune development in infants. J Nutr 135(1): 1–4. [CrossRef] [PubMed] [Google Scholar]
  • Foot M, Cruz TF, Clandinin MT. 1982. Influence of dietary fat on the lipid composition of rat brain synaptosomal and microsomal membranes. Biochem J 208(3): 631–640. [CrossRef] [PubMed] [Google Scholar]
  • Gallier S, et al. 2010. Using confocal laser scanning microscopy to probe the milk fat globule membrane and associated proteins. J Agric Food Chem 58(7): 4250–4257. [CrossRef] [PubMed] [Google Scholar]
  • Gallier S, et al. 2015. A novel infant milk formula concept: mimicking the human milk fat globule structure. Colloids Surf B Biointerfaces 136: 329–339. [CrossRef] [PubMed] [Google Scholar]
  • Garcia-Calatayud S, et al. 2005. Brain docosahexaenoic acid status and learning in young rats submitted to dietary long-chain polyunsaturated fatty acid deficiency and supplementation limited to lactation. Pediatr Res 57(5 Pt 1): 719–723. [CrossRef] [PubMed] [Google Scholar]
  • German JB, Dillard CJ. 2010. Saturated fats: a perspective from lactation and milk composition. Lipids 45(10): 915–923. [CrossRef] [PubMed] [Google Scholar]
  • Gibson RA, Muhlhausler B, Makrides M. 2011. Conversion of linoleic acid and alpha-linolenic acid to long-chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of life. Matern Child Nutr 7(Suppl. 2): 17–26. [Google Scholar]
  • Giovannini M, Riva E, Agostoni C. 1995. Fatty acids in pediatric nutrition. Pediatr Clin North Am 42(4): 861–877. [CrossRef] [PubMed] [Google Scholar]
  • Giuffrida F, et al. 2013. Quantification of phospholipids classes in human milk. Lipids 48(10): 1051–1058. [CrossRef] [PubMed] [Google Scholar]
  • Graf BA, et al. 2010. Age dependent incorporation of 14C-DHA into rat brain and body tissues after dosing various 14C-DHA-esters. Prostagland Leukot Essent Fatty Acids 83(2): 89–96. [CrossRef] [Google Scholar]
  • Greiner RS, et al. 1999. Rats with low levels of brain docosahexaenoic acid show impaired performance in olfactory-based and spatial learning tasks. Lipids 34(Suppl.): S239–S243. [CrossRef] [PubMed] [Google Scholar]
  • Grey KR, et al. 2013. Human milk cortisol is associated with infant temperament. Psychoneuroendocrinology 38(7): 1178–1185. [CrossRef] [PubMed] [Google Scholar]
  • Grosso G, et al. 2014. Omega-3 fatty acids and depression: scientific evidence and biological mechanisms. Oxidative Med Cell Longevity 2014: 313570. [CrossRef] [Google Scholar]
  • Guan J, et al. 2015. Long-term supplementation with beta serum concentrate (BSC), a complex of milk lipids, during post-natal brain development improves memory in rats. Nutrients 7(6): 4526–4541. [PubMed] [Google Scholar]
  • Guaraldi F, Salvatori G. 2012. Effect of breast and formula feeding on gut microbiota shaping in newborns. Front Cell Infect Microbiol 2: 94. [CrossRef] [PubMed] [Google Scholar]
  • Guillermo RB, et al. 2015. Supplementation with complex milk lipids during brain development promotes neuroplasticity without altering myelination or vascular density. Food Nutr Res 59: 25765. [CrossRef] [PubMed] [Google Scholar]
  • Gulpinar MA, Yegen BC. 2004. The physiology of learning and memory: role of peptides and stress. Curr Protein Pept Sci 5(6): 457–473. [Google Scholar]
  • Gundberg CM, Lian JB, Booth SL. 2012. Vitamin K-dependent carboxylation of osteocalcin: friend or foe? Adv Nutr 3(2): 149–157. [CrossRef] [PubMed] [Google Scholar]
  • Gurnida DA, et al. 2012. Association of complex lipids containing gangliosides with cognitive development of 6-month-old infants. Early Hum Dev 88(8): 595–601. [CrossRef] [PubMed] [Google Scholar]
  • Gustavsson M, et al. 2010. Maternal supplementation with a complex milk lipid mixture during pregnancy and lactation alters neonatal brain lipid composition but lacks effect on cognitive function in rats. Nutr Res 30(4): 279–289. [Google Scholar]
  • Hadley KB, et al. 2016. The essentiality of arachidonic acid in infant development. Nutrients 8(4): 216. [PubMed] [Google Scholar]
  • Hamazaki K, Hamazaki T, Inadera H. 2013. Abnormalities in the fatty acid composition of the postmortem entorhinal cortex of patients with schizophrenia, bipolar disorder, and major depressive disorder. Psychiatr Res 210(1): 346–350. [CrossRef] [Google Scholar]
  • Hamosh M, et al. 1985. Lipids in milk and the first steps in their digestion. Pediatrics 75(1 Pt 2): 146–150. [PubMed] [Google Scholar]
  • Harder T, et al. 2005. Duration of breastfeeding and risk of overweight: a meta-analysis. Am J Epidemiol 162(5): 397–403. [Google Scholar]
  • Hayatbakhsh MR, et al. 2012. Association of breastfeeding and adolescents’ psychopathology: a large prospective study. Breastfeed Med 7(6): 480–486. [Google Scholar]
  • Heid HW, Keenan TW. 2005. Intracellular origin and secretion of milk fat globules. Eur J Cell Biol 84(2-3): 245–258. [CrossRef] [PubMed] [Google Scholar]
  • Heikkila K, et al. 2014. Breastfeeding and educational achievement at age 5. Matern Child Nutr 10(1): 92–101. [Google Scholar]
  • Herba CM, et al. 2013. Breastfeeding and early brain development: the Generation R study. Matern Child Nutr 9(3): 332–349. [Google Scholar]
  • Hibbeln JR, et al. 2006. Healthy intakes of n-3 and n-6 fatty acids: estimations considering worldwide diversity. Am J Clin Nutr 83(6 Suppl.): 1483S–1493S. [CrossRef] [PubMed] [Google Scholar]
  • Horta BL, Loret de Mola C, Victora CG. 2015. Breastfeeding and intelligence: a systematic review and meta-analysis. Acta Paediatr 104(467): 14–19. [CrossRef] [PubMed] [Google Scholar]
  • Horwood LJ, Fergusson DM. 1998. Breastfeeding and later cognitive and academic outcomes. Pediatrics 101(1): E9. [Google Scholar]
  • Iacovou M, Sevilla A. 2013. Infant feeding: the effects of scheduled vs. on-demand feeding on mothers’ wellbeing and children’s cognitive development. Eur J Public Health 23(1): 13–19. [CrossRef] [PubMed] [Google Scholar]
  • Igarashi M, et al. 2009. Dietary n-6 PUFA deprivation for 15 weeks reduces arachidonic acid concentrations while increasing n-3 PUFA concentrations in organs of post-weaning male rats. Biochim Biophys Acta 1791(2): 132–139. [CrossRef] [PubMed] [Google Scholar]
  • Ikemoto A, et al. 2001. Reversibility of n-3 fatty acid deficiency-induced alterations of learning behavior in the rat: level of n-6 fatty acids as another critical factor. J Lipid Res 42(10): 1655–1663. [PubMed] [Google Scholar]
  • Innis SM. 2003. Perinatal biochemistry and physiology of long-chain polyunsaturated fatty acids. J Pediatr 143(4 Suppl.): S1–S8. [Google Scholar]
  • Innis SM. 2007. Dietary (n-3) fatty acids and brain development. J Nutr 137(4): 855–859. [CrossRef] [PubMed] [Google Scholar]
  • Jackson KM, Nazar AM. 2006. Breastfeeding, the immune response, and long-term health. J Am Osteopath Assoc 106(4): 203–207. [PubMed] [Google Scholar]
  • Jamieson EC, et al. 1999. Infant cerebellar gray and white matter fatty acids in relation to age and diet. Lipids 34(10): 1065–1071. [CrossRef] [PubMed] [Google Scholar]
  • Jensen RG, et al. 1990. Lipids of bovine and human milks: a comparison. J Dairy Sci 73(2): 223–240. [Google Scholar]
  • Kafouri S, et al. 2013. Breastfeeding and brain structure in adolescence. Int J Epidemiol 42(1): 150–159. [CrossRef] [PubMed] [Google Scholar]
  • Katakura M, et al. 2013. Omega-3 polyunsaturated fatty acids enhance neuronal differentiation in cultured rat neural stem cells. Stem Cells Int 2013: 490476. [CrossRef] [PubMed] [Google Scholar]
  • Kent JC, et al. 2006. Volume and frequency of breastfeedings and fat content of breast milk throughout the day. Pediatrics 117(3): e387–e395. [CrossRef] [PubMed] [Google Scholar]
  • Kessler RC, et al. 2009. The global burden of mental disorders: an update from the WHO World Mental Health (WMH) surveys. Epidemiol Psichiatr Soc 18(1): 23–33. [CrossRef] [PubMed] [Google Scholar]
  • Kitson AP, et al. 2016. Effect of dietary docosahexaenoic acid (DHA) in phospholipids or triglycerides on brain DHA uptake and accretion. J Nutr Biochem 33: 91–102. [CrossRef] [PubMed] [Google Scholar]
  • Klerman GL, Weissman MM. 1989. Increasing rates of depression. JAMA 261(15): 2229–2235. [CrossRef] [PubMed] [Google Scholar]
  • Kohlboeck G, et al. 2011. Effect of fatty acid status in cord blood serum on children’s behavioral difficulties at 10 years of age: results from the LISAplus study. Am J Clin Nutr 94(6): 1592–1599. [CrossRef] [PubMed] [Google Scholar]
  • Koletzko B, Rodriguez-Palmero M. 1999. Polyunsaturated fatty acids in human milk and their role in early infant development. J Mammary Gland Biol Neoplasia 4(3): 269–284. [CrossRef] [PubMed] [Google Scholar]
  • Koletzko B, Thiel I, Abiodun PO. 1992. The fatty acid composition of human milk in Europe and Africa. J Pediatr 120(4 Pt 2): S62–S70. [CrossRef] [PubMed] [Google Scholar]
  • Krabbendam L, et al. 2007. Relationship between DHA status at birth and child problem behaviour at 7 years of age. Prostagland Leukot Essent Fatty Acids 76(1): 29–34. [CrossRef] [Google Scholar]
  • Kracun I, et al. 1992. Gangliosides in the human brain development and aging. Neurochem Int 20(3): 421–431. [CrossRef] [PubMed] [Google Scholar]
  • Kris-Etherton PM, et al. 2000. Polyunsaturated fatty acids in the food chain in the United States. Am J Clin Nutr 71(1 Suppl.): 179S–188S. [CrossRef] [PubMed] [Google Scholar]
  • Kuipers RS, et al. 2005. High contents of both docosahexaenoic and arachidonic acids in milk of women consuming fish from lake Kitangiri (Tanzania): targets for infant formulae close to our ancient diet ? Prostagland Leukot Essent Fatty Acids 72(4): 279–288. [CrossRef] [PubMed] [Google Scholar]
  • Lassek WD, Gaulin SJ. 2014. Linoleic and docosahexaenoic acids in human milk have opposite relationships with cognitive test performance in a sample of 28 countries. Prostagland Leukot Essent Fatty Acids 91(5): 195–201. [CrossRef] [Google Scholar]
  • Lauritzen L, et al. 2016. DHA effects in brain development and function. Nutrients 8(1). [CrossRef] [PubMed] [Google Scholar]
  • Lefkowitz W, et al. 2005. Where does the developing brain obtain its docosahexaenoic acid? Relative contributions of dietary alpha-linolenic acid, docosahexaenoic acid, and body stores in the developing rat. Pediatr Res 57(1): 157–165. [CrossRef] [PubMed] [Google Scholar]
  • Leventakou V, et al. 2015. Breastfeeding duration and cognitive, language and motor development at 18 months of age: Rhea mother-child cohort in Crete, Greece. J Epidemiol Community Health 69(3): 232–239. [CrossRef] [PubMed] [Google Scholar]
  • Li R, Fein SB, Grummer-Strawn LM. 2008. Association of breastfeeding intensity and bottle-emptying behaviors at early infancy with infants’ risk for excess weight at late infancy. Pediatrics 122(Suppl. 2): S77–S84. [CrossRef] [PubMed] [Google Scholar]
  • Li R, Fein SB, Grummer-Strawn LM. 2010. Do infants fed from bottles lack self-regulation of milk intake compared with directly breastfed infants ? Pediatrics 125(6): e1386–e1393. [CrossRef] [PubMed] [Google Scholar]
  • Liu H, et al. 2014. Early supplementation of phospholipids and gangliosides affects brain and cognitive development in neonatal piglets. J Nutr 144(12): 1903–1909. [CrossRef] [PubMed] [Google Scholar]
  • Liu JJ, et al. 2015. Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease. Brain Res 1597: 220–246. [CrossRef] [PubMed] [Google Scholar]
  • Liu L, et al. 2014. Higher efficacy of dietary DHA provided as a phospholipid than as a triglyceride for brain DHA accretion in neonatal piglets. J Lipid Res 55(3): 531–539. [CrossRef] [PubMed] [Google Scholar]
  • Lopez C, Menard O. 2011. Human milk fat globules: polar lipid composition and in situ structural investigations revealing the heterogeneous distribution of proteins and the lateral segregation of sphingomyelin in the biological membrane. Colloids Surf B Biointerfaces 83(1): 29–41. [CrossRef] [PubMed] [Google Scholar]
  • Lopez C, et al. 2008. Phospholipid, sphingolipid, and fatty acid compositions of the milk fat globule membrane are modified by diet. J Agric Food Chem 56(13): 5226–5236. [CrossRef] [PubMed] [Google Scholar]
  • Lucas A, et al. 1981. Metabolic and endocrine responses to a milk feed in six-day-old term infants: differences between breast and cow’s milk formula feeding. Acta Paediatr Scand 70(2): 195–200. [CrossRef] [PubMed] [Google Scholar]
  • MacIntosh BA, et al. 2013. Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research. Br J Nutr 110(3): 559–568. [CrossRef] [PubMed] [Google Scholar]
  • Makrides M, et al. 1994. Fatty acid composition of brain, retina, and erythrocytes in breast- and formula-fed infants. Am J Clin Nutr 60(2): 189–194. [CrossRef] [PubMed] [Google Scholar]
  • Makrides M, et al. 1995. Changes in the polyunsaturated fatty acids of breast milk from mothers of full-term infants over 30 wk of lactation. Am J Clin Nutr 61(6): 1231–1233. [CrossRef] [PubMed] [Google Scholar]
  • Martinez M. 1992. Tissue levels of polyunsaturated fatty acids during early human development. J Pediatr 120(4 Pt 2): S129–S138. [CrossRef] [PubMed] [Google Scholar]
  • Martinez M, Mougan I. 1998. Fatty acid composition of human brain phospholipids during normal development. J Neurochem 71(6): 2528–2533. [CrossRef] [PubMed] [Google Scholar]
  • Martini M, Salari F, Altomonte I. 2016. The macrostructure of milk lipids: the fat globules. Crit Rev Food Sci Nutr 56(7): 1209–1221. [CrossRef] [PubMed] [Google Scholar]
  • Mather IH, Keenan TW. 1998. Origin and secretion of milk lipids. J Mammary Gland Biol Neoplasia 3(3): 259–273. [CrossRef] [PubMed] [Google Scholar]
  • Mathews SA, et al. 2002. Comparison of triglycerides and phospholipids as supplemental sources of dietary long-chain polyunsaturated fatty acids in piglets. J Nutr 132(10): 3081–3089. [CrossRef] [PubMed] [Google Scholar]
  • Mauch DH, et al. 2001. CNS synaptogenesis promoted by glia-derived cholesterol. Science 294(5545): 1354–1357. [Google Scholar]
  • McJarrow P, et al. 2009. Influence of dietary gangliosides on neonatal brain development. Nutr Rev 67(8): 451–463. [CrossRef] [PubMed] [Google Scholar]
  • McNamara RK. 2013. Deciphering the role of docosahexaenoic acid in brain maturation and pathology with magnetic resonance imaging. Prostagland Leukot Essent Fatty Acids 88(1): 33–42. [CrossRef] [Google Scholar]
  • McNamara RK, et al. 2007. Selective deficits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder. Biol Psychiatry 62(1): 17–24. [CrossRef] [PubMed] [Google Scholar]
  • Michaelsen KF, et al. 1992. Serum bone gamma-carboxyglutamic acid protein in a longitudinal study of infants: lower values in formula-fed infants. Pediatr Res 31(4 Pt 1): 401–405. [CrossRef] [PubMed] [Google Scholar]
  • Michaelsen KF, Lauritzen L, Mortensen EL. 2009. Effects of breast-feeding on cognitive function. Adv Exp Med Biol 639: 199–215. [CrossRef] [PubMed] [Google Scholar]
  • Michalski MC, et al. 2005. Size distribution of fat globules in human colostrum, breast milk, and infant formula. J Dairy Sci 88(6): 1927–1940. [Google Scholar]
  • Michalski MC, et al. 2006. The supramolecular structure of milk fat influences plasma triacylglycerols and fatty acid profile in the rat. Eur J Nutr 45(4): 215–224. [CrossRef] [PubMed] [Google Scholar]
  • Michalski MC, et al. 2013. Multiscale structures of lipids in foods as parameters affecting fatty acid bioavailability and lipid metabolism. Prog Lipid Res 52(4): 354–373. [CrossRef] [PubMed] [Google Scholar]
  • Mitchell RW, Hatch GM. 2011. Fatty acid transport into the brain: of fatty acid fables and lipid tails. Prostagland Leukot Essent Fatty Acids 85(5): 293–302. [CrossRef] [PubMed] [Google Scholar]
  • Monnikes H, et al. 1997. Pathways of Fos expression in locus ceruleus, dorsal vagal complex, and PVN in response to intestinal lipid. Am J Physiol 273(6 Pt 2): R2059–R2071. [Google Scholar]
  • Montgomery SM, Ehlin A, Sacker A. 2006. Breast feeding and resilience against psychosocial stress. Arch Dis Child 91(12): 990–994. [CrossRef] [PubMed] [Google Scholar]
  • Morgan C, et al. 1998. Fatty acid balance studies in term infants fed formula milk containing long-chain polyunsaturated fatty acids. Acta Paediatr 87(2): 136–142. [CrossRef] [PubMed] [Google Scholar]
  • Moriguchi T, Greiner RS, Salem N Jr. 2000. Behavioral deficits associated with dietary induction of decreased brain docosahexaenoic acid concentration. J Neurochem 75(6): 2563–2573. [CrossRef] [PubMed] [Google Scholar]
  • Morris MD, Chaikoff IL. 1961. Concerning incorporation of labelled cholesterol, fed to the mothers, into brain cholesterol of 20-day-old suckling rats. J Neurochem 8: 226–229. [CrossRef] [PubMed] [Google Scholar]
  • Moukarzel S, et al. 2018. Milk fat globule membrane supplementation in formula-fed rat pups improves reflex development and may alter brain lipid composition. Sci Rep 8(1): 15277. [CrossRef] [PubMed] [Google Scholar]
  • Muskiet FAJ. Frontiers in neuroscience. pathophysiology and evolutionary aspects of dietary fats and long-chain polyunsaturated fatty acids across the life cycle. In Montmayeur JP, Le Coutre J, eds. Fat detection: taste, texture, and post ingestive effects. Boca Raton (FL): CRC Press/Taylor & Francis, Taylor & Francis Group, LLC, 2010. [Google Scholar]
  • Muskiet FA, et al. 2004. Is docosahexaenoic acid (DHA) essential? Lessons from DHA status regulation, our ancient diet, epidemiology and randomized controlled trials. J Nutr 134(1): 183–186. [CrossRef] [PubMed] [Google Scholar]
  • Muskiet FA, et al. 2006. Long-chain polyunsaturated fatty acids in maternal and infant nutrition. Prostaglandins Leukot Essent Fatty Acids 75(3): 135–144. [CrossRef] [PubMed] [Google Scholar]
  • Neuringer M, et al. 1986. Biochemical and functional effects of prenatal and postnatal omega 3 fatty acid deficiency on retina and brain in rhesus monkeys. Proc Natl Acad Sci U S A 83(11): 4021–4025. [CrossRef] [PubMed] [Google Scholar]
  • Novak EM, Dyer RA, Innis SM. 2008. High dietary omega-6 fatty acids contribute to reduced docosahexaenoic acid in the developing brain and inhibit secondary neurite growth. Brain Res 1237: 136–145. [CrossRef] [PubMed] [Google Scholar]
  • O’Brien JS, Sampson EL. 1965. Lipid composition of the normal human brain: gray matter, white matter, and myelin. J Lipid Res 6(4): 537–544. [PubMed] [Google Scholar]
  • Oddy WH, et al. 2010. The long-term effects of breastfeeding on child and adolescent mental health: a pregnancy cohort study followed for 14 years. J Pediatr 156(4): 568–574. [CrossRef] [PubMed] [Google Scholar]
  • Ohlsson L, et al. 2014. Postprandial effects on plasma lipids and satiety hormones from intake of liposomes made from fractionated oat oil: two randomized crossover studies. Food Nutr Res 58. [Google Scholar]
  • Ortega-Anaya J, Jimenez-Flores R. 2019. Symposium review: the relevance of bovine milk phospholipids in human nutrition-evidence of the effect on infant gut and brain development. J Dairy Sci 102(3): 2738–2748. [Google Scholar]
  • Oshida K, et al. 2003. Effects of dietary sphingomyelin on central nervous system myelination in developing rats. Pediatr Res 53(4): 589–593. [CrossRef] [PubMed] [Google Scholar]
  • Oury F, et al. 2013. Maternal and offspring pools of osteocalcin influence brain development and functions. Cell 155(1): 228–241. [CrossRef] [PubMed] [Google Scholar]
  • Palmano K, et al. 2015. The role of gangliosides in neurodevelopment. Nutrients 7(5): 3891–3913. [PubMed] [Google Scholar]
  • Park EJ, et al. 2005. Diet-induced changes in membrane gangliosides in rat intestinal mucosa, plasma and brain. J Pediatr Gastroenterol Nutr 40(4): 487–495. [CrossRef] [PubMed] [Google Scholar]
  • Plagemann A, et al. 2005. Impact of early neonatal breast-feeding on psychomotor and neuropsychological development in children of diabetic mothers. Diabetes Care 28(3): 573–578. [CrossRef] [PubMed] [Google Scholar]
  • Polanczyk GV, et al. 2015. Annual research review: a meta-analysis of the worldwide prevalence of mental disorders in children and adolescents. J Child Psychol Psychiatry 56(3): 345–365. [CrossRef] [PubMed] [Google Scholar]
  • Posse de Chaves E, Sipione S. 2010. Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction. FEBS Lett 584(9):1748–1759. [CrossRef] [PubMed] [Google Scholar]
  • Qawasmi A, et al. 2012. Meta-analysis of long-chain polyunsaturated fatty acid supplementation of formula and infant cognition. Pediatrics 129(6): 1141–1149. [CrossRef] [PubMed] [Google Scholar]
  • Ramprasath VR, et al. 2013. Enhanced increase of omega-3 index in healthy individuals with response to 4-week n-3 fatty acid supplementation from krill oil versus fish oil. Lipids Health Dis 12: 178. [CrossRef] [PubMed] [Google Scholar]
  • Reis MM, et al. 2016. Effect of dietary complex lipids on the biosynthesis of piglet brain gangliosides. J Agric Food Chem 64(6): 1245–1255. [CrossRef] [PubMed] [Google Scholar]
  • Robson LG, et al. 2010. Omega-3 polyunsaturated fatty acids increase the neurite outgrowth of rat sensory neurones throughout development and in aged animals. Neurobiol Aging 31(4): 678–687. [Google Scholar]
  • Saarela T, Kokkonen J, Koivisto M. 2005. Macronutrient and energy contents of human milk fractions during the first six months of lactation. Acta Paediatr 94(9): 1176–1181. [CrossRef] [PubMed] [Google Scholar]
  • Saher G, et al. 2005. High cholesterol level is essential for myelin membrane growth. Nat Neurosci 8(4): 468–475. [CrossRef] [PubMed] [Google Scholar]
  • Salem N Jr., et al. 1996. Arachidonic and docosahexaenoic acids are biosynthesized from their 18-carbon precursors in human infants. Proc Natl Acad Sci U S A 93(1): 49–54. [CrossRef] [PubMed] [Google Scholar]
  • Salmenpera L, et al. 1988. Effects of feeding regimen on blood glucose levels and plasma concentrations of pancreatic hormones and gut regulatory peptides at 9 months of age: comparison between infants fed with milk formula and infants exclusively breast-fed from birth. J Pediatr Gastroenterol Nutr 7(5): 651–656. [CrossRef] [PubMed] [Google Scholar]
  • Sanders TA. 2000. Polyunsaturated fatty acids in the food chain in Europe. Am J Clin Nutr 71(1 Suppl.): 176S–178S. [CrossRef] [PubMed] [Google Scholar]
  • Savino F, et al. 2009. Breast milk hormones and their protective effect on obesity. Int J Pediatr Endocrinol 2009: 327505. [PubMed] [Google Scholar]
  • Schipper L, et al. 2013. Postnatal dietary fatty acid composition permanently affects the structure of hypothalamic pathways controlling energy balance in mice. Am J Clin Nutr 98(6): 1395–1401. [CrossRef] [PubMed] [Google Scholar]
  • Schipper L, et al. 2016. Reducing dietary intake of linoleic acid of mouse dams during lactation increases offspring brain n-3 LCPUFA content. Prostagland Leukot Essent Fatty Acids 110: 8–15. [CrossRef] [PubMed] [Google Scholar]
  • Schipper L, et al. 2016. A postnatal diet containing phospholipids, processed to yield large, phospholipid-coated lipid droplets, affects specific cognitive behaviors in healthy male mice. J Nutr 146(6): 1155–1161. [CrossRef] [PubMed] [Google Scholar]
  • Simmer K, Schulzke SM, Patole S. 2008. Long-chain polyunsaturated fatty acid supplementation in preterm infants. Cochrane Database Syst Rev (1): Cd000375. [Google Scholar]
  • Simonin C, Ruegg M, Sidiropoulos D. 1984. Comparison of the fat content and fat globule size distribution of breast milk from mothers delivering term and preterm. Am J Clin Nutr 40(4): 820–826. [CrossRef] [PubMed] [Google Scholar]
  • Singh H. 2006. The milk fat globule membrane — A biophysical system for food applications. Curr Opin Colloid Interface Sci 11(2): 154–163. [Google Scholar]
  • Skjodt H, et al. 1985. Vitamin D metabolites regulate osteocalcin synthesis and proliferation of human bone cells in vitro. J Endocrinol 105(3): 391–396. [CrossRef] [PubMed] [Google Scholar]
  • Slupsky CM, et al. 2017. Postprandial metabolic response of breast-fed infants and infants fed lactose-free vs regular infant formula: a randomized controlled trial. Sci Rep 7(1): 3640. [CrossRef] [PubMed] [Google Scholar]
  • Tanaka K, et al. 2013. The pilot study: sphingomyelin-fortified milk has a positive association with the neurobehavioural development of very low birth weight infants during infancy, randomized control trial. Brain Dev 35(1): 45–52. [CrossRef] [PubMed] [Google Scholar]
  • Timby N, et al. 2014. Neurodevelopment, nutrition, and growth until 12 mo of age in infants fed a low-energy, low-protein formula supplemented with bovine milk fat globule membranes: a randomized controlled trial. Am J Clin Nutr 99(4): 860–868. [CrossRef] [PubMed] [Google Scholar]
  • Ulven SM, et al. 2011. Metabolic effects of krill oil are essentially similar to those of fish oil but at lower dose of EPA and DHA, in healthy volunteers. Lipids 46(1): 37–46. [CrossRef] [PubMed] [Google Scholar]
  • van Aken GA. 2010. Relating food emulsion structure and composition to the way it is processed in the gastrointestinal tract and physiological responses: what are the opportunities? Food Biophys 5(4): 258–283. [Google Scholar]
  • van Driel M, van Leeuwen JPTM. 2014. Vitamin D endocrine system and osteoblasts. BoneKEy Rep 3: 493. [PubMed] [Google Scholar]
  • Vasquez-Garibay EM, et al. 2019. Serum concentration of appetite-regulating hormones of mother-infant dyad according to the type of feeding. Food Sci Nutr 7(2): 869–874. [CrossRef] [PubMed] [Google Scholar]
  • Vickers MH, et al. 2009. Supplementation with a mixture of complex lipids derived from milk to growing rats results in improvements in parameters related to growth and cognition. Nutr Res 29(6): 426–435. [Google Scholar]
  • Victora CG, et al. 2015. Association between breastfeeding and intelligence, educational attainment, and income at 30 years of age: a prospective birth cohort study from Brazil. Lancet Global Health 3(4): e199–e205. [CrossRef] [Google Scholar]
  • Wang B. 2012. Molecular mechanism underlying sialic acid as an essential nutrient for brain development and cognition. Adv Nutr 3(3): 465S–472S. [CrossRef] [PubMed] [Google Scholar]
  • Wang B, et al. 2003. Brain ganglioside and glycoprotein sialic acid in breastfed compared with formula-fed infants. Am J Clin Nutr 78(5): 1024–1029. [CrossRef] [PubMed] [Google Scholar]
  • Wang B, et al. 2007. Dietary sialic acid supplementation improves learning and memory in piglets. Am J Clin Nutr 85(2): 561–569. [CrossRef] [PubMed] [Google Scholar]
  • Watkins BA, et al. 2000. Dietary ratio of (n-6)/(n-3) polyunsaturated fatty acids alters the fatty acid composition of bone compartments and biomarkers of bone formation in rats. J Nutr 130(9): 2274–2284. [CrossRef] [PubMed] [Google Scholar]
  • World Health Organization (WHO) 2017. 10 facts on breastfeeding. At: http://www.who.int/features/factfiles/breastfeeding/en/. [Google Scholar]
  • Wijendran V, et al. 2002. Efficacy of dietary arachidonic acid provided as triglyceride or phospholipid as substrates for brain arachidonic acid accretion in baboon neonates. Pediatr Res 51(3): 265–272. [CrossRef] [PubMed] [Google Scholar]
  • Williard DE, et al. 2001. Docosahexaenoic acid synthesis from n-3 polyunsaturated fatty acids in differentiated rat brain astrocytes. J Lipid Res 42(9): 1368–1376. [PubMed] [Google Scholar]
  • Wolmarans P. 2009. Background paper on global trends in food production, intake and composition. Ann Nutr Metab 55(1–3): 244–272. [CrossRef] [PubMed] [Google Scholar]
  • Wood KE, et al. 2013. Incorporating macadamia oil and butter to reduce dietary omega-6 polyunsaturated fatty acid intake. Nutr Diet 70(2): 94–100. [Google Scholar]
  • Wood KE, et al. 2014. A low omega-6 polyunsaturated fatty acid (n-6 PUFA) diet increases omega-3 (n-3) long chain PUFA status in plasma phospholipids in humans. Prostagland Leukot Essent Fatty Acids 90(4): 133–138. [CrossRef] [Google Scholar]
  • Wooding FB. 1971. The mechanism of secretion of the milk fat globule. J Cell Sci 9(3): 805–821. [Google Scholar]
  • Yam KY, et al. 2019. Increasing availability of omega-3 fatty acid in the early-life diet prevents the early-life stress-induced cognitive impairments without affecting metabolic alterations. FASEB J 33(4): 5729–5740. [CrossRef] [PubMed] [Google Scholar]
  • Ye A, Anema SG, Singh H. 2008. Changes in the surface protein of the fat globules during homogenization and heat treatment of concentrated milk. J Dairy Res 75(3): 347–353. [CrossRef] [PubMed] [Google Scholar]
  • Youdim KA, Martin A, Joseph JA. 2000. Essential fatty acids and the brain: possible health implications. Int J Dev Neurosci 18(4-5): 383–399. [CrossRef] [PubMed] [Google Scholar]
  • Yuhas R, Pramuk K, Lien EL. 2006. Human milk fatty acid composition from nine countries varies most in DHA. Lipids 41(9): 851–858. [CrossRef] [PubMed] [Google Scholar]
  • Zeisel SH. 2000. Choline: needed for normal development of memory. J Am Coll Nutr 19(5 Suppl.): 528S–531S. [CrossRef] [PubMed] [Google Scholar]
  • Zeisel SH. 2004. Nutritional importance of choline for brain development. J Am Coll Nutr 23(6 Suppl.): 621S–626S. [CrossRef] [PubMed] [Google Scholar]
  • Zhang J, Liu Q. 2015. Cholesterol metabolism and homeostasis in the brain. Protein Cell 6(4): 254–264. [CrossRef] [PubMed] [Google Scholar]
  • Zou XQ, et al. 2012. Human milk fat globules from different stages of lactation: a lipid composition analysis and microstructure characterization. J Agric Food Chem 60(29): 7158–7167. [CrossRef] [PubMed] [Google Scholar]

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