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Table 3

Reported bioactivities of peptides derived from canola protein.

Bioactivity Study details Reference

Angiotensin Peptides having IY, RIY, VW and VWIS sequences with ACE inhibiting Marczak et al., 2003
I-converting  activity was generated from enzyme-assisted hydrolysis of rapeseed meal.
enzyme (ACE) Sequences of VSV and FL from ACE inhibitory protein hydolysate from Wu and Muir, 2008
inhibiting,  canola meal.
in vitro and Rapeseed protein hydrolysed with Alcalase generated RIY peptide has high Pedroche et al., 2004
in vivo  potency as an antihypertensive component in spontaneously hypertensive rat models.
The potential of generating ACEI peptides from Hydrolysis of B. napus Yoshie-Stark et al., 2006
 proteins (alkali extracted and acid precipitated) with endoprotease.

Antioxidative Ethanol soluble peptides of rapeseed meal protein hydrolysates possessed
 antioxidant activities as indicated by reducing power, hydroxyl and DPPH Zhang et al., 2008
 radical scavenging activity and ferrous-induced phosphotidyl choline
 oxidation inhibition, and antithrombotic activity.

Antifungal Napins recovered from commercial canola showed strong activity in Noi et al., 2012
 suppressing growth of Fusarium langsethiae.

Oral feeding of RIY peptide of canola hydrolysate exhibited anorexic effects
Affecting  on fasting ddY male mice and the same peptide was capable of blocking Marczaket al., 2003
food intake  cholecystokinin-1 (CCK1) receptor antagonist lorglumide and decrease
 of gastric emptying rate by blocking lorglumide.

Affecting Canola protein isolates exerted preventive effects on the early onset of insulin Mariotti et al., 2008
blood sugar  resistance in rats fed with high saturated fat and sucrose diets.

Rapeseed protein hydrolysate with mostly <1 kDa molecules enhanced the
 growth of insect cell Sf9 line in serum-free media more effectively than Deparis et al., 2003
 bovine lactalbumin hydrolysate without affecting the general metabolism
Affecting  of the cells.
cell growth Rapeseed protein hydrolysates containing peptides of 0.5 to 5 kDa enhanced Farges-Haddani et al., 2006
 CHO C5 cell line growth rate.
Canola meal hydrolysate from Alcalase showed anti-inflammatory Rivera et al., 2016
 anti-wrinkle activity by inhibiting myleperoxidase and elastase activity.

Antiviral Alcalase-assisted hydrolysis of canola protein generated peptides capable of Yust et al., 2004
 inhibiting human immunodeficiency virus (HIV) protease.

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