Open Access
Table 3
Reported bioactivities of peptides derived from canola protein.
Bioactivity | Study details | Reference |
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Angiotensin | • Peptides having IY, RIY, VW and VWIS sequences with ACE inhibiting | Marczak et al., 2003 |
I-converting | activity was generated from enzyme-assisted hydrolysis of rapeseed meal. | |
enzyme (ACE) | • Sequences of VSV and FL from ACE inhibitory protein hydolysate from | Wu and Muir, 2008 |
inhibiting, | canola meal. | |
in vitro and | • Rapeseed protein hydrolysed with Alcalase generated RIY peptide has high | Pedroche et al., 2004 |
in vivo | potency as an antihypertensive component in spontaneously hypertensive rat models. | |
• The potential of generating ACEI peptides from Hydrolysis of B. napus | Yoshie-Stark et al., 2006 | |
proteins (alkali extracted and acid precipitated) with endoprotease. | ||
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Antioxidative | • Ethanol soluble peptides of rapeseed meal protein hydrolysates possessed | |
antioxidant activities as indicated by reducing power, hydroxyl and DPPH | Zhang et al., 2008 | |
radical scavenging activity and ferrous-induced phosphotidyl choline | ||
oxidation inhibition, and antithrombotic activity. | ||
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Antifungal | • Napins recovered from commercial canola showed strong activity in | Noi et al., 2012 |
suppressing growth of Fusarium langsethiae. | ||
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• Oral feeding of RIY peptide of canola hydrolysate exhibited anorexic effects | ||
Affecting | on fasting ddY male mice and the same peptide was capable of blocking | Marczaket al., 2003 |
food intake | cholecystokinin-1 (CCK1) receptor antagonist lorglumide and decrease | |
of gastric emptying rate by blocking lorglumide. | ||
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Affecting | • Canola protein isolates exerted preventive effects on the early onset of insulin | Mariotti et al., 2008 |
blood sugar | resistance in rats fed with high saturated fat and sucrose diets. | |
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• Rapeseed protein hydrolysate with mostly <1 kDa molecules enhanced the | ||
growth of insect cell Sf9 line in serum-free media more effectively than | Deparis et al., 2003 | |
bovine lactalbumin hydrolysate without affecting the general metabolism | ||
Affecting | of the cells. | |
cell growth | • Rapeseed protein hydrolysates containing peptides of 0.5 to 5 kDa enhanced | Farges-Haddani et al., 2006 |
CHO C5 cell line growth rate. | ||
• Canola meal hydrolysate from Alcalase showed anti-inflammatory | Rivera et al., 2016 | |
anti-wrinkle activity by inhibiting myleperoxidase and elastase activity. | ||
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Antiviral | • Alcalase-assisted hydrolysis of canola protein generated peptides capable of | Yust et al., 2004 |
inhibiting human immunodeficiency virus (HIV) protease. |
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