Rapeseed oil and magnesium manipulations affect the seizure threshold to kainate in mice | OCL

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Table 1.

Effects magnesium-deficient diets on threshold to kainate-induced seizures

Diets		Threshold to kainate-induced seizures (mg/kg)	Threshold to kainate-induced seizure after acute MgCl₂ injection (mg/kg)
Mg+	Commercial diet	45.0±2.2^*a (reference threshold)

Mg-	ALA poor diet (corn/sunflower)	14.5±3.1^*b	31.0±2.0^*d
Mg-	ALA rich diet (rapeseed)	17.5±1.6^*c	27.2±1.5^*d

Evaluations were performed on 10 mice in each experimental group and condition. Mg+, normal magnesium-containing diet; Mg-, magnesium-deficient diets; ALA, alpha-linolenic acid.*, p<0.05;

^{*a, *b,*c}

groups significantly different p<0.05;

^*d

groups acutely injected versus corresponding non injected groups significantly different p<0.05

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