| Issue |
OCL
Volume 18, Number 1, Janvier-Février 2011
Dossier : Lipides et inflammation
|
|
|---|---|---|
| Page(s) | 34 - 38 | |
| Section | Nutrition – Santé | |
| DOI | https://doi.org/10.1051/ocl.2011.0362 | |
| Published online | 15 January 2011 | |
Dénutrition cancéreuse et inflammation : effet des acides gras polyinsaturés n-3
1
Inserm U921, nutrition, croissance et cancer, 37032 Tours, France
2
Université François-Rabelais, faculté de médecine, bâtiment Dutrochet, 10, boulevard Tonnellé, 37032 Tours, France
3
CHRU de Bretonneau, 37044 Tours, France
4
IUT, 37082
Tours, France
*
jean-francois.dumas@univ-tours.fr
Abstract
Undernutrition is frequently seen in cancer and is considered as a bad prognostic factor. The mechanisms involved in this complex syndrome are not fully understood. Systemic inflammation plays an important role in the occurrence and/or development of cancer-associated undernutrition. Although it is essential to counteract cancer-associated undernutrition, modalities for nutritional treatment are still discussed. It has been shown that nutritional supplementation with n-3 polyunsaturated fatty acid could be beneficial in patients.
Key words: cachexia / cytokines / metabolism / mitochondria
© John Libbey Eurotext 2011
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