EDP Sciences logo
Submit your paper
Search
Menu
Home All issues Volume 30 (2023) OCL, 30 (2023) 22 References
Open Access
Review
Issue
OCL
Volume 30, 2023
Article Number 22
Number of page(s) 18
Section Nutrition - Health
DOI https://doi.org/10.1051/ocl/2023023
Published online 03 November 2023
  • Adams J, Chen ZP, Van Denderen BJ, et al. 2004. Intrasteric control of AMPK via thegamma1 subunit AMP allosteric regulatory site. Protein Sci 13 (1): 155–165. [CrossRef] [PubMed] [Google Scholar]
  • Agus DB, Gambhir SS, Pardridge WM, et al. 1997. Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters. J Clin Inves 100 (11): 2842–2848. [CrossRef] [PubMed] [Google Scholar]
  • Allaman I, Bélanger M, Magistretti PJ. 2011. Astrocyte-neuron metabolic relationships: for better and for worse. Trends Neurosci 34 (2): 76–87. [CrossRef] [PubMed] [Google Scholar]
  • Amen DG, Harris WS, Kidd PM, Meysami S, Raji CA. 2017. Quantitative erythrocyte omega-3 EPA plus DHA levels are related to higher regional cerebral blood flow on brain SPECT. J Alzheimers Dis 58 (4): 1189–1199. [CrossRef] [PubMed] [Google Scholar]
  • Andrisse S, Patel GD, Chen JE, et al. 2013. ATM and GLUT1-S490 phosphorylation regulate GLUT1 mediated transport in skeletal muscle. PLoS One (6): e66027. [CrossRef] [PubMed] [Google Scholar]
  • Bailyes EM, Navé BT, Soos MA, Orr SR, Hayward AC, Siddle K. 1997. Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting. Biochem J 327 (Pt 1)(Pt 1): 209–215. [CrossRef] [PubMed] [Google Scholar]
  • Barceló-Coblijn G, Collison LW, Jolly CA, et al. 2005. Dietary α-linolenic acid increases brain but not heart and liver docosahexaenoic acid levels. Lipids 40: 787–798. [CrossRef] [PubMed] [Google Scholar]
  • Barger PM, Browning AC, Garner AN, Kelly DP. 2001. p38 mitogen-activated protein kinase activates peroxisome proliferator-activated receptor alpha: a potential role in the cardiac metabolic stress response. J Biol Chem 276 (48): 44495–44501. [CrossRef] [PubMed] [Google Scholar]
  • Bent S, Bertoglio K, Hendren RL. 2009. Omega-3 fatty acids for autistic spectrum disorder: a systematic review. J Autism Dev Disord 39 (8): 1145–1154. [CrossRef] [PubMed] [Google Scholar]
  • Bewicz-Binkowska D, Zgorzynska E, Dziedzic B, Walczewska A. 2019. Docosahexaenoic acid (DHA) inhibits FADS2 expression in astrocytes but increases survival of neurons co-cultured with DHA-enriched astrocytes. Int J Mol Cell Med 8 (3): 232–240. [PubMed] [Google Scholar]
  • Beyer RE. 1994. The role of ascorbate in antioxidant protection of biomembranes: interaction with vitamin E and coenzyme Q. J Bioenerg Biomembr 26 (4): 349–358. [CrossRef] [PubMed] [Google Scholar]
  • Biojone C, Casarotto PC, Joca SR, Castrén E. 2015. Interplay between nitric oxide and brain-derived neurotrophic factor in neuronal plasticity. CNS Neurol Disord Drug Targets 14 (8): 979–987. [CrossRef] [PubMed] [Google Scholar]
  • Bourre JM, Francois M, Youyou A, et al. 1989. The effects of dietary alpha-linolenic acid on the composition of nerve membranes, enzymatic activity, amplitude of electrophysiological parameters, resistance to poisons and performance of learning tasks in rats. J Nutr 119 (12): 1880–1892. [CrossRef] [PubMed] [Google Scholar]
  • Bourre JM. 2006. Effects of nutrients (in food) on the structure and function of the nervous system: update on dietary requirements for brain. Part 1: micronutrients. J Nutr Health Aging 10: 377–385. [PubMed] [Google Scholar]
  • Brandes N, Schmitt S, Jakob U. 2009. Thiol-based redox switches in eukaryotic proteins. Antioxid Redox Signal 11 (5): 997–1014. [Google Scholar]
  • Brenna JT. 2002. Efficiency of conversion of alpha-linolenic acid to long chain n-3 fatty acids in man. Curr Opin Clin Nutr Metab Care 5 (2): 127–132. [CrossRef] [PubMed] [Google Scholar]
  • Brenna JT, Diau GY. 2007. The influence of dietary docosahexaenoic acid and arachidonic acid on central nervous system polyunsaturated fatty acid composition. Prostaglandins Leukot Essent Fatty Acids 77 (5-6): 247–250. [CrossRef] [PubMed] [Google Scholar]
  • Bunn R, Jensen M, Reed B. 1999. Protein interactions with the glucose transporter binding protein GLUT-1CBP that provide a link between GLUT-1 and the cytoskeleton. Mol Biol Cell 10 (4): 819–832. [CrossRef] [PubMed] [Google Scholar]
  • Burdge GC, Wootton SA. 2002. Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women. Br J Nutr 88 (4): 411–420. [CrossRef] [PubMed] [Google Scholar]
  • Campbell SE, Mehan KA, Tunstall RJ, Febbraio MA, Cameron-Smith D. 2003. 17beta-estradiol upregulates the expression of peroxisome proliferator-activated receptor alpha and lipid oxidative genes in skeletal muscle. J Mol Endocrinol 31 (1): 37–45. [CrossRef] [PubMed] [Google Scholar]
  • Capper EA, Marshall LA. 2001. Mammalian phospholipases A(2): mediators of inflammation, proliferation and apoptosis. Prog Lipid Res 40 (3): 167–197. [CrossRef] [PubMed] [Google Scholar]
  • Carlström K, Eriksson A, Stege R, Rannevik G. 1990. Relationship between serum testosterone and sex hormone-binding globulin in adult men with intact or absent gonadal function. Int J Androl 13 (1): 67–73. [CrossRef] [PubMed] [Google Scholar]
  • Castro MA, Beltran FA, Brauchi S, Concha II. 2009. A metabolic switch in brain: glucose and lactate metabolism modulation by ascorbic acid. J Neurochem 10 (2): 423–440. [CrossRef] [PubMed] [Google Scholar]
  • Caviedes A, Varas-Godoy M, Lafourcade C, et al. 2017. Endothelial nitric oxide synthase is present in dendritic spines of neurons in primary cultures. Front Cell Neurosci 11: 180. [CrossRef] [PubMed] [Google Scholar]
  • Cazaubon SM, Ramos-Morales F, Fischer S, Schweighoffer F, Strosberg AD, Couraud PO. 1994. Endothelin induces tyrosine phosphorylation and GRB2 association of Shc in astrocytes. J Biol Chem 269 (40): 24805–24809. [CrossRef] [PubMed] [Google Scholar]
  • Celermajer DS, Sorensen KE, Spiegelhalter DJ, Georgakopoulos D, Robinson J, Deanfield JE. 1994. Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women. J Am Coll Cardiol 24 (2): 471–476. [CrossRef] [PubMed] [Google Scholar]
  • Chaban VV, Lakhter AJ, Micevych P. 2004. A membrane estrogen receptor mediates intracellular calcium release in astrocytes. Endocrinology 145 (8): 3788–3795. [CrossRef] [PubMed] [Google Scholar]
  • Chambliss KL, Simon L, Yuhanna IS, Mineo C, Shaul PW. 2005. Dissecting the basis of nongenomic activation of endothelial nitric oxide synthase by estradiol: role of ERalpha domains with known nuclear functions. Mol Endocrinol 19 (2): 277–289. [CrossRef] [PubMed] [Google Scholar]
  • Chen WG, Chang Q, Lin Y, et al. 2003. Derepression of BDNF transcription involves calcium-dependent phosphorylation of Me CP2. Science 302 (5646): 885–889. [CrossRef] [PubMed] [Google Scholar]
  • Chen S, Murphy J, Toth R, Campbell DG, Morrice NA, Mackintosh C. 2008. Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators. Biochem J 409 (2): 449–459. [CrossRef] [PubMed] [Google Scholar]
  • Chen L, Bi J, Nakai M, et al. 2010. Expression of basigin in reproductive tissues of estrogen receptor-{alpha} or −{beta} null mice. Reproduction 139 (6): 1057–1066. [CrossRef] [PubMed] [Google Scholar]
  • Cheng C, Cohen M, Wang J, Bondy C. 2001. Estrogen augments glucose transporter and IGF1 expression in primate cerebral cortex. FASEB J 15 (6): 907–915. [CrossRef] [PubMed] [Google Scholar]
  • Chernausek, SD. 1993. Insulin-like growth factor-I (IGF-I) production by astroglial cells: Regulation and importance for epidermal growth factor-induced cell replication. J Neurosci Res 34 (2): 189–197. [CrossRef] [PubMed] [Google Scholar]
  • Cho HP, Nakamura MT, Clarke SD. 1999. Cloning, expression, and nutritional regulation of the mammalian Delta-6 desaturase. J Biol Chem 274 (1): 471–477. [CrossRef] [PubMed] [Google Scholar]
  • Choeiri C, Staines W, Miki T, Seino S, Messier C. 2005. Glucose transporter plasticity during memory processing. Neuroscience 130 (3): 591–600. [CrossRef] [PubMed] [Google Scholar]
  • Culmsee C, Monnig J, Kemp BE, Mattson MP. 2001. AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation. J Mol Neurosci 17 (1): 45–58. [CrossRef] [PubMed] [Google Scholar]
  • Cunningham SK, Loughlin T, Culliton M, McKenna TJ. 1984. Plasma sex hormone-binding globulin levels decrease during the second decade of life irrespective of pubertal status. J Clin Endocrinol Metab 58 (5): 915–918. [CrossRef] [PubMed] [Google Scholar]
  • Cura AJ, Carruthers A. 2012. AMP kinase regulation of sugar transport in brain capillary endothelial cells during acute metabolic stress. Am J Physiol Cell Physiol 303 (8): C806– C814. [CrossRef] [PubMed] [Google Scholar]
  • Custódio TF, Paulsen PA, Frain KM, Pedersen BP. 2021. Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family. Life Sci Alliance 4 (4):e202000858. [CrossRef] [PubMed] [Google Scholar]
  • Daskalopoulos R, Korcok J, Tao L, Wilson JX. 2002. Accumulation of intracellular ascorbate from dehydroascorbic acid by astrocytes is decreased after oxidative stress and restored by propofol. Glia 39 (2): 124–132. [CrossRef] [PubMed] [Google Scholar]
  • Deckelbaum RJ, Worgall TS, Seo T, 2006. n-3 fatty acids and gene expression. Am J Clin Nutr 83: 1520S–1525S. [CrossRef] [PubMed] [Google Scholar]
  • Delplanque B, 2017. Acides gras oméga-3 : de l’acide α-linolénique (ALA) à l’acide docosahexaénoïque (DHA). Lipid Nutri+ 34. [Google Scholar]
  • Diep QN, Amiri F, Touyz RM, et al. 2002. PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation. Hypertension 40 (6): 866–871. [CrossRef] [PubMed] [Google Scholar]
  • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. 1999. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399 (6736): 601–605. [CrossRef] [PubMed] [Google Scholar]
  • Dziedzic B, Bewicz-Binkowska D, Zgorzynska E, et al. 2018. DHA upregulates FADS2 expression in primary cortical astrocytes exposed to vitamin A. Physiol Res 67 (4): 663–668. [CrossRef] [PubMed] [Google Scholar]
  • Edmond J, Robbins RA, Bergstrom JD, Cole RA, de Vellis J, 1987. Capacity for substrate utilization in oxidative metabolism by neurons, astrocytes, and oligodendrocytes from developing brain in primary culture. Neurosci Res 18 (4): 551–561. [CrossRef] [PubMed] [Google Scholar]
  • Emory University Health Sciences Center. 2004. Patients with uncontrolled epilepsy have low levels of fatty acids. ScienceDaily. [Google Scholar]
  • Engström K, Saldeen AS, Yang B, Mehta JL, Saldeen T. 2009. Effect of fish oils containing different amounts of EPA, DHA, and antioxidants on plasma and brain fatty acids and brain nitric oxide synthase activity in rats. Ups J Med Sci 114 (4): 206–213. [CrossRef] [PubMed] [Google Scholar]
  • Ernest MJ, Kim KH. 1974. Regulation of rat liver glycogen synthetase D. Role of glucose 6-phosphate and enzyme sulfhydryl groups in activity and glycogen binding. J Biol Chem. 249 (16): 5011–5018. [Google Scholar]
  • Fellows LK, Boutelle MG, Fillenz M. 1993. Physiological stimulation increases nonoxidative glucose metabolism in the brain of the freely moving rat. J Neurochem 60 (4): 258–263. [Google Scholar]
  • Fernhoff NB, Derbyshire ER, Underbakke ES, Marletta MA. 2012. Heme-assisted S-nitrosation desensitizes ferric soluble guanylate cyclase to nitric oxide. J Biol Chem. 287 (51): 43053–43062. [Google Scholar]
  • Fiacco TA, McCarthy KD. 2004. Intracellular astrocyte calcium waves in situ increase the frequency of spontaneous AMPA receptor currents in CA1 pyramidal neurons. J Neurosci 24 (3): 722–732. [CrossRef] [PubMed] [Google Scholar]
  • Fox PT, Raichle ME, Mintun MA, Dence C. 1988. Nonoxidative Glucose consumption during focal physiologic neural activity. Science 241 (4864): 462–464. [CrossRef] [PubMed] [Google Scholar]
  • Furukawa K, Mattson MP. 1998. Secreted amyloid precursor protein alpha selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: involvement of cyclic GMP. Neuroscience 83 (2): 429–438. [CrossRef] [PubMed] [Google Scholar]
  • Gadalla AE, Pearson T, Currie AJ, et al. 2004. AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus. J Neurochem 88 (5): 1272–1282. [CrossRef] [PubMed] [Google Scholar]
  • Galea E, Feinstein DL, Reis DJ. 1992. Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures. Proc Nati Acad Sci USA 89 (22): 10945–10949. [CrossRef] [PubMed] [Google Scholar]
  • Garcia-Segura LM, Sanz A, Mendez P. 2006. Cross-talk between IGF- I and estradiol in the brain: focus on neuroprotection. Neuroendocrinology 84 (4): 275–279. [CrossRef] [PubMed] [Google Scholar]
  • Gardner OS, Dewar BJ, Earp HS, Samet JM, Graves LM. 2003. Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation. J Biol Chem 278 (47): 46261–46269. [CrossRef] [PubMed] [Google Scholar]
  • Ge L, Gordon JS, Hsuan C, Stenn K, Prouty SM. 2003. Identification of the delta-6 desaturase of human sebaceous glands: expression and enzyme activity. J Invest Dermatol 120 (5): 707–714. [CrossRef] [PubMed] [Google Scholar]
  • Geraghty KM, Chen S, Harthill JE, et al. 2007. Regulation of multisite phosphorylation and 14- 3–3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR. Biochem J 407 (2): 231–241. [CrossRef] [PubMed] [Google Scholar]
  • Gerhard M, Roddy MA, Creager SJ, Creager MA. 1996. Aging progressively impairs endothelium-dependent vasodilation in forearm resistance vessels of humans. Hypertension 27 (4): 849–853. [CrossRef] [PubMed] [Google Scholar]
  • Gibson RA, Neumann MA, Lien EL, Boyd KA, Tu WC. 2013. Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. Prostaglandins Leukot Essent Fatty Acids 88 (1): 139–146. [CrossRef] [PubMed] [Google Scholar]
  • Giltay EJ, Gooren LJG, Toorians AW, Katan MB, Zock PL. 2004. Docosahexanoic acid concentrations are higher in women than in men because of estrogenic effects. Am J Clin Nutr 80 (5): 1167–1174. [CrossRef] [PubMed] [Google Scholar]
  • Gingerich S, Krukoff TL. 2008. Activation of ERβ increases levels of phosphorylated nNOS and NO production through a Src/PI3K/Akt-dependent pathway in hypothalamic neurons. Neuropharmacology 55: 878–885. [CrossRef] [PubMed] [Google Scholar]
  • Greene RA. 2000. Estrogen and cerebral blood flow: a mechanism to explain the impact of estrogen on the incidence and treatment of Alzheimer’s disease. Int J Fertil Womens Med 45 (4): 253–257. [PubMed] [Google Scholar]
  • Grohe C, Kann S, Fink L, et al. 2004. 17 Beta-estradiol regulates nNOS and eNOS activity in the hippocampus. Neuroreport 15 (1): 89–93. [CrossRef] [PubMed] [Google Scholar]
  • Gu H, Maeda H, Moon JJ, et al. 2000. New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway. Mol Cell Biol 20 (19): 7109–7120. [CrossRef] [PubMed] [Google Scholar]
  • Guix FX, Uribesalgo I, Coma M, Munoz FJ. 2005. The physiology and pathophysiology of nitric oxide in the brain. Prog Neurobiol 76 (2): 126–152. [CrossRef] [PubMed] [Google Scholar]
  • Gur RC, Mozley LH, Mozley PD, et al. 1995. Sex differences in regional cerebral glucose metabolism during a resting state. Science 267 (5197): 528–531. [CrossRef] [PubMed] [Google Scholar]
  • Halestrap AP, Price NT. 1999. The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. Biochem J 343(Pt2): 281–299. [CrossRef] [PubMed] [Google Scholar]
  • Hammond GL. 2016. Plasma steroid-binding proteins: primary gatekeepers of steroid hormone action. J Endocrinol 230 (1): R13– R25. [CrossRef] [PubMed] [Google Scholar]
  • Harbeby E, Jouin M, Alessandri JM, et al. 2012. n −3 PUFA status affects expression of genes involved in neuroenergetics differently in the fronto-parietal cortex compared to the CA1 area of the hippocampus: effect of rest and neuronal activation in the rat. Prostaglandins Leukot Essent Fatty Acids 86 (6): 211–220. [CrossRef] [PubMed] [Google Scholar]
  • Harbeby E, Pifferi F, Jouin M, et al. xx xx 2012. [Google Scholar]
  • N-3 fatty acids, neuronal activity and energy metabolism in the brain. Oléagineux, Corps Gras, Lipides 19 xxxx (4): 238–244. [Google Scholar]
  • Harman SM, Metter EJ, Tobin JD, Pearson J, Blackman MR Baltimore. 2001. Longitudinal study of aging. longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore longitudinal study of aging. J Clin Endocrinol Metabol 86: xxxx 724–731. [CrossRef] [PubMed] [Google Scholar]
  • Harrell CS, Burgado J, Kelly SD, Neigh GN. 2014. Ovarian steroids influence cerebral glucose transporter expression in a region - and isoform-specific pattern. J Neuroendocrinol 26 (4): 217–225. [CrossRef] [PubMed] [Google Scholar]
  • Harrison FE, May JM. 2009. Vitamin C function in the brain: vital role of the ascorbate transporter SV CT2. Free Radic Biol Med 46 (6): 719–730. [CrossRef] [PubMed] [Google Scholar]
  • Hart CD, Flozak AS, Simmons RA. 1998. Modulation of glucose transport in fetal rat lung: a sexual dimorphism. Am J Respir Cell Mol Biol 19 (1): 63–70. [CrossRef] [PubMed] [Google Scholar]
  • Hartmann M, Heumann R, Lessmann V. 2021. Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses. EMBO J 20: 21. [Google Scholar]
  • Herbert Z, Göthe S, Caldwell JD, et al. 2005. Identification of sex hormone-binding globulin in the human hypothalamus. Neuroendocrinology 81 (5): 287–293. [CrossRef] [PubMed] [Google Scholar]
  • Hernandez-Garzón E, Fernandez AM, Perez-Alvarez A, et al. 2016. The insulin-like growth factor I receptor regulates glucose transport by astrocytes. Glia 64 (11): 1962–1971. [CrossRef] [PubMed] [Google Scholar]
  • Hewitt SC, Li Y, Li L, Korach KS. 2010. Estrogen-mediated regulation of Igf1 transcription and uterine growth involves direct binding of estrogen receptor alpha to estrogen-responsive elements. J Biol Chem 285 (4): 2676–2685. [CrossRef] [PubMed] [Google Scholar]
  • Hirvonen J, Virtanen KA, Nummenmaa L, et al. 2011. Effects of insulin on brain glucose metabolism in impaired glucose tolerance. Diabetes 60 (2): 443–447. [CrossRef] [PubMed] [Google Scholar]
  • Howarth C, Gleeson P, Attwell D. 2012. Updated energy budgets for neural computation in the neocortex and cerebellum. J Cereb Blood Flow Metab 32 (7): 1222–1232. [CrossRef] [PubMed] [Google Scholar]
  • Huang S, Taylor C, Zahradka P. 2021. Novel mechanisms related to DHA’s atheroprotective effects in endothelial cells: eNOS activity is regulated by DHA via p38MAPK and MSK. Curr Dev Nutr 7;5(Suppl 2): 22. [CrossRef] [PubMed] [Google Scholar]
  • Huang S, Taylor CG, Zahradka P. 2023. Growth state-dependent activation of eNOS in response to DHA: involvement of p38 MAPK. Int J Mol Sci 24 (9): 8346. [CrossRef] [PubMed] [Google Scholar]
  • Hubbard SR, Till JH. 2000. Protein tyrosine kinase structure and function. Annu Rev Biochem 69:373–398 [Google Scholar]
  • Huffman J, Hoffmann C, Taylor GT. 2017. Integrating insulin-like growth factor 1 and sex hormones into neuroprotection: Implications for diabetes. World J Diabetes 8 (2): 45–55. [CrossRef] [PubMed] [Google Scholar]
  • Hwang JK, Yu HN, Noh EM, et al. 2017. DHA blocks TPA-induced cell invasion by inhibiting MMP-9 expression via suppression of the PPARγ/NF-κB pathway in MCF-7 cells. Oncol Lett 13: 243–249. [CrossRef] [PubMed] [Google Scholar]
  • Innis SM, Dyer RA. 2002. Brain astrocyte synthesis of docosahexaenoic acid from n-3 fatty acids is limited at the elongation of docosapentaenoic acid. J Lipid Res 43 (9): 1529–1536. [CrossRef] [PubMed] [Google Scholar]
  • Isenovic ER, Divald A, Milivojevic N, Grgurevic T, Fisher SE, Sowers JR. 2003. Interactive effects of insulin-like growth factor- 1 and beta-estradiol on endothelial nitric oxide synthase activity in rat aortic endothelial cells. Metabolism 52 (4): 482–487. [CrossRef] [PubMed] [Google Scholar]
  • Ishizuka Y, Kakiya N, Witters LA, et al. 2013. AMP-activated protein kinase counteracts brain-derived neurotrophic factor-induced mammalian target of rapamycin complex 1 signaling in neurons. J Neurochem 127 (1): 66–77. [CrossRef] [PubMed] [Google Scholar]
  • Jasnow AM, Mong JA, Romeo RD, Pfaff DW. 2007. Estrogenic regulation of gene and protein expression within the amygdala of female mice. Endocrine 32 (3): 271–279. [CrossRef] [PubMed] [Google Scholar]
  • Joost H, Thorens B. 2001. The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review). Mo l Membr Biol 18 (4): 247–256. [Google Scholar]
  • Jueptner M, Weiller C. 1995. Review: does measurement of regional cerebral blood flow reflect synaptic activity? Implications for PET and fMRI. Neuroimage 2 (2): 148–156. [CrossRef] [PubMed] [Google Scholar]
  • Jump DB, 2002. The biochemistry of n-3 polyunsaturated fatty acids. J Biol Chem 277: 8755–8758. [CrossRef] [PubMed] [Google Scholar]
  • Juul A, Bang P, Hertel NT, et al. 1994. Serum insulin-like growth factor-I in 1030 healthy children, adolescents, and adults: relation to age, sex, stage of puberty, testicular size, and body mass index. J Clin Endocrinol Metab 78 (3): 744–752. [PubMed] [Google Scholar]
  • Kahlert S, Nuedling S, van Eickels M, Vetter H, Meyer R, Grohe C. 2000. Estrogen receptor alpha rapidly activates the IGF-1 receptor pathway. J Bio Chem 275: 18447–18453. [CrossRef] [Google Scholar]
  • Kato S, Endoh H, Masuhiro Y, et al. 2011. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270 (5241): 1491–1494. [Google Scholar]
  • Khorchid A, Ikura M. 2002. How calpain is activated by calcium. Nat Struct Biol 9 (4): 239–241. [CrossRef] [PubMed] [Google Scholar]
  • Kim JA, Formoso G, Li Y, et al. 2007. Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and Fyn. J Biol Chem 282 (18): 13736–13745. [CrossRef] [PubMed] [Google Scholar]
  • Kim IJ, Kim SJ, Kim YK. 2009. Age- and sex-associated changes in cerebral glucose metabolism in normal healthy subjects: statistical parametric mapping analysis of F-18 fluorodeoxyglucose brain positron emission tomography. Acta Radiol 50 (10): 1169–1174. [CrossRef] [PubMed] [Google Scholar]
  • Kim HY, Choi HJ, Lim JS, et al. 2011. Emerging role of Akt substrate protein AS160 in the regulation of AQP2 translocation. Am J Physiol Renal Physiol 301 (1): F151–161. [CrossRef] [PubMed] [Google Scholar]
  • Kitson AP, Stroud CK, Stark KD. 2010. Elevated production of docosahexaenoic acid in females: potential molecular mechanisms. Lipids 45 (3): 209–224. [CrossRef] [PubMed] [Google Scholar]
  • Kitson AP, Marks KA, Shaw B, Mutch DM, Stark KD. 2013. Treatment of ovariectomized rats with 17β-estradiol increases hepatic delta-6 desaturase enzyme expression and docosahexaenoic acid levels in hepatic and plasma phospholipids. Prostaglandins Leukot Essent Fatty Acids 89 (2-3): 81–88. [CrossRef] [PubMed] [Google Scholar]
  • Kleinridders A. 2016. Deciphering Brain Insulin Receptor and Insulin-Like Growth Factor 1 Receptor Signalling. J Neuroendocrinol 28 (11): 10.1111/jne. 12433. [CrossRef] [Google Scholar]
  • Ko GY, Kelly PT. 1999. Nitric oxide acts as a postsynaptic signaling molecule in calcium/calmodulin-induced synaptic potentiation in hippocampal CA1Pyramidal neurons. J Neurosci 19 (16): 6784–6794. [CrossRef] [PubMed] [Google Scholar]
  • Komeima K, Hayashi Y, Naito Y, Watanabe Y. 2000. Inhibition of neuronal nitric-oxide synthase by calcium/ calmodulin-dependent protein kinase IIalpha through Ser847 phosphorylation in NG 108–15 neuronal cells. J Biol Chem 275 (36): 28139–28143. [CrossRef] [PubMed] [Google Scholar]
  • Kowalewski MP, Dyson MT, Manna PR, Stocco DM. 2009. Involvement of peroxisome proliferator-activated receptor gamma in gonadal steroidogenesis and steroidogenic acute regulatory protein expression. Reprod Fertil Dev 21 (7): 909–922. [CrossRef] [PubMed] [Google Scholar]
  • Kramer HF, Taylor EB, Witczak CA, Fujii N, Hirshman MF, Goodyear LJ. 2007. Calmodulin-binding domain of AS160 regulates contraction- but not insulin-stimulated glucose uptake in skeletal muscle. Diabetes 56 (12): 2854–2862. [CrossRef] [PubMed] [Google Scholar]
  • Kumagai AK, Dwyer KJ, Pardridge WM. 1994. Differential glycosylation of the GLUT1 glucose transporter in brain capillaries and choroid plexus. Biochim Biophys Acta 1193 (1): 24–30. [CrossRef] [PubMed] [Google Scholar]
  • de Labra C, Rivadulla C, Espinosa N, Dasilva M, Cao R, Cudeiro J. 2009. Different sources of nitric oxide mediate neurovascular coupling in the lateral geniculate nucleus of the cat. Front Syst Neurosci 3: 9. [CrossRef] [PubMed] [Google Scholar]
  • Lattka E, Eggers S, Moeller G, et al. 2010. A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor E LK1. J Lipid Res 51 (1): 182–191. [CrossRef] [PubMed] [Google Scholar]
  • Lee M-C., Ting KK, Adams S, Brew BJ, Chung R, Guillemin GJ. 2010. Characterisation of the Expression of NMDA Receptors in Human Astrocytes. PLoS ONE 5 (11): e14123. [CrossRef] [PubMed] [Google Scholar]
  • Liu G, Bibus DM, Bode AM, Ma WY, Holman RT, Dong Z. 2001. Omega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells. Proc Natl Acad Sci U S A 98 (13): 7510–7515. [CrossRef] [PubMed] [Google Scholar]
  • Liu RM, van Groen T, Katre A, et al. 2011. Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimer’s disease. Neurobiol Aging 32 (6): 1079–1089. [CrossRef] [PubMed] [Google Scholar]
  • Liu M, Kuhel DG, Shen L, Hui DY, Woods SC. 2012. Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice. Am J Physiol Regul Integr Comp Physiol 303 (9): R903–908. [CrossRef] [PubMed] [Google Scholar]
  • Mac Innes KJ, Brown KA, Hunger NI, Simpson ER. 2012. Regulation of LKB1 expression by sex hormones in adipocytes. Int J Obes 36 (7): 982–985. [CrossRef] [PubMed] [Google Scholar]
  • Madathil SK, Carlson SW, Brelsfoard JM, Ye P, D’Ercole AJ. 2013. Astrocyte-specific overexpression of insulin-like growth factor-1 protects hippocampal neurons and reduces behavioral deficits following traumatic brain injury in mice. PLoS ONE 8 (6):e 67204. [Google Scholar]
  • Maggio M, Lauretani F, Basaria S, et al. 2008. Sex hormone binding globulin levels across the adult lifespan in women-the role of body mass index and fasting insulin. J Endocrinol Invest 31 (7): 597–601. [CrossRef] [PubMed] [Google Scholar]
  • Magistretti PJ, Pellerin L. 1997. Metabolic coupling during activation. A cellular view. Adv Exp Med Biol 413: 161–166. [CrossRef] [PubMed] [Google Scholar]
  • Magistretti PJ. 2009. Role of glutamate in neuron-glia metabolic coupling. Am J Clin Nutr 90 (3): 875S–880S. [CrossRef] [PubMed] [Google Scholar]
  • Majou D. 2015. Alzheimer’s disease: origins, mechanisms, people at risk and prevention by DHA (omega-3 fatty acid). Paris: Actia Editions. [Google Scholar]
  • Majou D. 2018. Evolution of the human brain: the key roles of DHA (omega-3 fatty acid) and Δ6-desaturase gene. OCL 25 (4): A401. [CrossRef] [EDP Sciences] [Google Scholar]
  • Majou D. 2021. Synthesis of DHA (omega-3 fatty acid): FADS2 gene polymorphisms and regulation by PPARα. OCL 28 (43). [CrossRef] [EDP Sciences] [Google Scholar]
  • Magnusardottir AR, Steingrimsdottir L, Thorgeirsdottir H, Gunnlaugsson G, Skuladottir GV. 2009. Docosahexaenoic acid in red blood cells of women of reproductive age is positively associated with oral contraceptive use and physical activity. Prostaglandins Leukot Essent Fatty Acids. 80 (1): 27–32. [CrossRef] [Google Scholar]
  • Markesbery WR. 1999. The role of oxidative stress in Alzheimer disease. Arch Neurol 56 (12): 1449–1452. [CrossRef] [PubMed] [Google Scholar]
  • Marko DM, Foran G, Vlavcheski F, et al. 2020. Interleukin-6 treatment results in GLUT4 translocation and AMPK phosphorylation in neuronal SH-SY5Y Cells. Cells 9 (5): 1114. [CrossRef] [PubMed] [Google Scholar]
  • Matsuzaka T, Shimano H, Yahagi N, et al. 2002. Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha. J Lipid Res 43 (1): 107–114. [PubMed] [Google Scholar]
  • McCullough LD, Zeng Z, Li H, Landree LE, McFadden J, Ronnett GV. 2005. Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke. J Biol Chem 280 (21): 20493–20502. [CrossRef] [PubMed] [Google Scholar]
  • McNamara RK, Liu Y, Jandacek R, Rider T, Tso P. 2008. The aging human orbitofrontal cortex: decreasing polyunsaturated fatty acid composition and associated increases in lipogenic gene expression and stearoyl-CoA desaturase activity. Prostaglandins Leukot Essent Fatty Acids 78 (4-5): 293–304. [CrossRef] [PubMed] [Google Scholar]
  • Mergenthaler P, Lindauer U, Dienel GA, Meisel A. 2013. Sugar for the brain: the role of glucose in physiological and pathological brain function. Trends Neurosci 36 (10): 587–597. [CrossRef] [PubMed] [Google Scholar]
  • Milte CM, Parletta N, Buckley JD, Coates AM, Young RM, Howe PR. 2012. Eicosapentaenoic and docosahexaenoic acids, cognition, and behavior in children with attention-deficit/hyperactivity disorder: a randomized controlled trial. Nutrition 28 (6): 670–677. [CrossRef] [PubMed] [Google Scholar]
  • Min J. 2007. 17 β-estradiol-stimulated eNOS gene transcriptional activation is regulated through the estrogen-responsive element in eNOS promoter. Biotechnol Bioprocess Eng 12 (4): 446–449. [CrossRef] [Google Scholar]
  • Mohankumar SK, Taylor CG, Zahradka P. 2012. Domain-dependent modulation of insulin-induced AS160 phosphorylation and glucose uptake by Ca2+/calmodulin-dependent protein kinase II in L6 myotubes. Cell Signal 24 (1): 302–308. [CrossRef] [PubMed] [Google Scholar]
  • Moncada S, Palmer RM, Higgs EA. 1991. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43 (2): 109–142. [PubMed] [Google Scholar]
  • Moore SA, Yoder E, Murphy S, Dutton GR, Spector AA. 1991. Astrocytes, not neurons, produce docosahexaenoic acid (22 :6 ω3) and arachidonic acid (20 :4 ω6). J Neurochem 56 (2): 518–524. [CrossRef] [PubMed] [Google Scholar]
  • Moreno M, Lombardi A, Silvestri E, et al. 2010. PPARs: nuclear receptors controlled by, and controlling, nutrient handling through nuclear and cytosolic signaling. PPAR Res 2010: 435689. [CrossRef] [Google Scholar]
  • Muramatsu T. 2016. Basigin (CD147), a multifunctional transmembrane glycoprotein with various binding partners. J Biochem 159 (5): 481–490. [CrossRef] [PubMed] [Google Scholar]
  • Naeini Z, Toupchian O, Vatannejad A, et al. 2020. Effects of DHA-enriched fish oil on gene expression levels of p53 and NF-κB and PPAR-γ activity in PBMCs of patients with T2DM: a randomized, double-blind, clinical trial. Nutr Metab Cardiovasc Dis 30 (3): 441–447. [CrossRef] [PubMed] [Google Scholar]
  • Nagai K, Yoshida S, Konishi H. 2014. Gender differences in the gene expression profiles of glucose transporter GLUT class I and SGLT in mouse tissues. Pharmazie 69 (11): 856–859. [PubMed] [Google Scholar]
  • Nakamura MT, Nara TY. 2004. Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases. Ann Rev Nutr 24: 345–376. [CrossRef] [PubMed] [Google Scholar]
  • Neggers YH, Kim YH, Kim EK, et al. 2009. Mental retardation is associated with plasma omega-3 fatty acid levels and the omega-3/omega-6 ratio in children. Asia Pac J Clin Nutr 18 (1): 22–28. [PubMed] [Google Scholar]
  • Nehlig, A, Porrino LJ, Crane AM, Sokoloff L. 1985. Local cerebral glucose utilization in normal female rats: variations during the estrous cycle and comparison with males. J Cereb Blood Flow Metab 5 (3): 393–400. [CrossRef] [PubMed] [Google Scholar]
  • Nelson BS, Springer RC, Daniel JM. 2014. Antagonism of brain insulin-like growth factor-1 receptors blocks estradiol effects on memory and levels of hippocampal synaptic proteins in ovariectomized rats. Psychopharmacology (Berl) 231 (5): 899–907. [CrossRef] [PubMed] [Google Scholar]
  • Nguyen LN, Ma D, Shui G, et al. 2014. Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid. Nature 509 (7501): 503–506. [CrossRef] [PubMed] [Google Scholar]
  • Nishijima T, Piriz J, Duflot S, et al. 2010. Neuronal activity drives localized blood-brain-barrier transport of serum insulin-like growth factor-I into the CNS. Neuron 67 (5): 834–846. [CrossRef] [PubMed] [Google Scholar]
  • Nwankwo JO, Spector AA, Domann FE. 2003. A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency. J Lipid Res 44 (12): 2311–2319. [CrossRef] [PubMed] [Google Scholar]
  • O’Brien J, Kla KM, Hopkins IB, Malecki EA, McKenna MC. 2007. Kinetic Parameters and Lactate Dehydrogenase Isozyme Activities Support Possible Lactate Utilization by Neurons. Neurochem Res 32 (465): 597–607. [CrossRef] [PubMed] [Google Scholar]
  • O’Neill CM, Minihane AM. 2017. The impact of fatty acid desaturase genotype on fatty acid status and cardiovascular health in adults. Proc Nutr Soc 76 (1): 64–75. [CrossRef] [PubMed] [Google Scholar]
  • Ohta Y, Nishikimi M. 1999. Random nucleotide substitutions in primate nonfunctional gene for L-gulono-gamma-lactone oxidase, the missing enzyme in L-ascorbic acid biosynthesis. Biochim Biophys Acta 1472 (1-2): 408–411. [CrossRef] [PubMed] [Google Scholar]
  • Orth M, Bellosta S. 2012, Cholesterol: its regulation and role in central nervous system disorders. Cholesterol 2012 (3): 292598. [CrossRef] [Google Scholar]
  • Panzer C, Wise S, Fantini G, et al. 2006. Impact of oral contraceptives on sex hormone-binding globulin and androgen levels: a retrospective study in women with sexual dysfunction. J Sex Med 3 (1): 104–113. [CrossRef] [PubMed] [Google Scholar]
  • Pardridge WM, Mietus LJ. 1979. Transport of steroid hormones through the rat blood-brain barrier. Primary role of albumin-bound hormone. J Clin Invest 64 (1): 145–154. [CrossRef] [PubMed] [Google Scholar]
  • Park S, Nozaki K, Smith JA, Krause JS, Banik NL. 2014. Cross-talk between IGF-1 and estrogen receptors attenuates intracellular changes in ventral spinal cord 4.1 motoneuron cells because of interferon-gamma exposure. J Neurochem 128 (6): 904–918. [CrossRef] [PubMed] [Google Scholar]
  • Parkash J, d’Anglemont de Tassigny X, Bellefontaine N,xxx xx et al. 2010. [Google Scholar]
  • Phosphorylation of N-Methyl-d-aspartic acid receptor-associated neuronal nitric oxide synthase depends on estrogens and modulates hypothalamic nitric oxide production during the ovarian cycle. Endocrinology 151 (6):xxxx 2723 − 2735. [Google Scholar]
  • Parlak H, Ozkan A, Dilmac S, Tanriover G, Ozsoy O,Agar A. 2018. Neuronal nitric oxide synthase phosphorylation induced by docosahexaenoic acid protects dopaminergic neurons in an experimental model of Parkinson’s disease. Folia Histochem Cytobiol 56 (1): 27–37. [PubMed] [Google Scholar]
  • Paulson OB, Hasselbalch SG, Rostrup E, Knudsen GM, Pelligrino D. 2010. Cerebral blood flow response to functional activation. J Cereb Blood Flow Metab 30 (1): 2–14. [CrossRef] [PubMed] [Google Scholar]
  • Pawlak J, Karolczak M, Krust A, Chambon P, Beyer C. 2005. Estrogen receptor-alpha is associated with the plasma membrane of astrocytes and coupled to the MAP/Src-kinase pathway. Glia 50 (3): 270–275. [CrossRef] [PubMed] [Google Scholar]
  • Pédrono F, Blanchard H, Kloareg M, et al. 2010. The fatty acid desaturase 3 gene encodes for different FADS3 protein isoforms in mammalian tissues. J Lipid Res 51 (3): 472–479. [CrossRef] [PubMed] [Google Scholar]
  • Pellerin L, Magistretti PJ. 2003. Food for thought: challenging the dogmas. J Cereb Blood Flow Metab 23 (11): 1282–1286. [CrossRef] [PubMed] [Google Scholar]
  • Pérez-Escuredo J, Van Hée VF, Sboarina M, et al. 2016. Monocarboxylate transporters in the brain and in cancer. Biochim Biophys Acta 1863 (10): 2481–2497. [CrossRef] [PubMed] [Google Scholar]
  • Pierre K, Pellerin L. 2005. Monocarboxylate transporters in the central nervous system: distribution, regulation and function. J Neurochem 94 (1): 1–14. [CrossRef] [PubMed] [Google Scholar]
  • Pifferi F, Roux F, Langelier B, et al. 2005. (N-3) polyunsaturated fatty acid deficiency reduced expression of both isoforms of the brain glucose transporter GLUT1 in rats. J Nutr 135 (9): 2241–2246. [CrossRef] [PubMed] [Google Scholar]
  • Pifferi F, Jouin M, Alessandri JM, et al. 2010. n-3 long-chain fatty acids and regulation of glucose transport in two models of rat brain endothelial cells. Neurochem Int 56 (5): 703–710. [CrossRef] [PubMed] [Google Scholar]
  • Pifferi F, Dorieux O, Castellano CA, et al. 2015. Long-chain n-3 PUFAs from fish oil enhance resting state brain glucose utilization and reduce anxiety in an adult nonhuman primate, the grey mouse lemur. J Lipid Res 6 (8): 1511–1518. [CrossRef] [PubMed] [Google Scholar]
  • Prichard J, Rothman D, Novotny E, et al. 1991. Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation. Proc Nat Acad Sci USA 88 (13): 5829–5831. [CrossRef] [PubMed] [Google Scholar]
  • Purich DL, Fromm HJ, Rudolph FB. 1973. The hexokinases: kinetic, physical, and regulatory properties. Adv Enzymol Relat Areas Mol Biol 39: 249–326. [PubMed] [Google Scholar]
  • Rameau GA, Tukey DS, Garcin-Hosfield ED, et al. 2007. Biphasic coupling of neuronal nitric oxide synthase phosphorylation to the NMDA receptor regulates AMPA receptor trafficking and neuronal cell death. J Neurosci 27 (13): 3445–3455. [CrossRef] [PubMed] [Google Scholar]
  • Rasgon NL, Silverman D, Siddarth P, et al. 2005. Estrogen use and brain metabolic change in postmenopausal women. Neurobiol Aging 26 (2): 229–235. [CrossRef] [PubMed] [Google Scholar]
  • Reed BC, Cefalu C, Bellaire BH, et al. 2005. GLUT1CBP(TIP2/GIPC1) interactions with GLUT1 and myosin VI: evidence supporting an adapter function for GLUT1CBP. Mol Biol Cell 16 (9): 4183–4201. [CrossRef] [PubMed] [Google Scholar]
  • Reis PA, de Albuquerque CFG, Gutierrez TM, Silva AR, de Castro Faria Neto HC. 2017. Role of nitric oxide synthase in the function of the central nervous system under normal and infectious conditions. In:Saravi SSS, Nitric Oxide Synthase − Simple Enzyme-Complex Roles. London: InTech, pp. 55–70. [Google Scholar]
  • Revest JM, Le Roux A, Roullot-Lacarrière V, et al. 2014. BDNF-TrkB signaling through Erk1/2 MAPK phosphorylation mediates the enhancement of fear memory induced by glucocorticoids. Mol Psychiatry 19 (9): 1001–1009. [CrossRef] [PubMed] [Google Scholar]
  • Rodriguez JJ, Olabarria M, Chvatal A, Verkhratsky A. 2009. Astroglia in dementia and Alzheimer’s disease. Cell Death Differ 16 (3): 378–385. [CrossRef] [PubMed] [Google Scholar]
  • Rogers NH, Witczak CA, Hirshman MF, Goodyear LJ, Greenberg AS. 2009. Estradiol stimulates Akt, AMP-activated protein kinase (AMPK) and TBC1D1/4, but not glucose uptake in rat soleus. Biochem Biophys Res Commun 382 (4): 646–650. [CrossRef] [PubMed] [Google Scholar]
  • Rosa AO, Rapoport SI. 009. Intracellular- and extracellular-derived Ca(2+) influence phospholipase A(2)-mediated fatty acid release from brain phospholipids. Biochim Biophys Acta 1791 (8): 697–705. [Google Scholar]
  • Roselli CE, Liu M, Hurn PD. 2009. Brain aromatization: classical roles and new perspectives. Semin Reprod Med 27 (3): 207–217. [CrossRef] [PubMed] [Google Scholar]
  • Roy CS, Sherrington CS. 1890. On the regulation of the blood-supply of the brain. J Physiol 11: 85–158. [CrossRef] [PubMed] [Google Scholar]
  • Rumsey SC, Kwon O, Xu GW, Burant CF, Simpson I, Levine M. 1997. Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid. J Biol Chem 272 (30): 18982–18989. [CrossRef] [PubMed] [Google Scholar]
  • Russo C, Dolcini V, Salis S, et al. 2002. Signal transduction through tyrosine-phosphorylated carboxy-terminal fragments of APP via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer’s disease brain. Ann N Y Acad Sci 973: 323–333. [CrossRef] [PubMed] [Google Scholar]
  • Russo VC, Gluckman PD, Feldman EL, Werther GA. 2005. The insulin-like growth factor system and its pleiotropic functions in brain. Endocrine Reviews 26 (7): 916–943. [CrossRef] [PubMed] [Google Scholar]
  • Sakamoto K, Holman GD. 2008. Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic. Am J Physiol: Endocrinol Metab 295 (1): E29– E37. [CrossRef] [PubMed] [Google Scholar]
  • Saleh TM, Connell BJ, Legge C, Cribb AE. 2005. Estrogen synthesis in the central nucleus of the amygdala following middle cerebral artery occlusion: role in modulating neurotransmission. Neuroscience 135 (4): 1141–1153. [CrossRef] [PubMed] [Google Scholar]
  • Sandoval D, Sisley SR. 2015. Brain GLP-1 and insulin sensitivity. Mol Cell Endocrinol 418(Pt 1): 27–32. [CrossRef] [PubMed] [Google Scholar]
  • Sappey-Marinier D, Calabrese G, Fein G, Hugg JW, Biggins C, Weiner MW. 1992. Effect of photic stimulation on human visual cortex lactate and phosphates using 1H and 31P magnetic resonance spectroscopy. J Cereb Blood Flow Metab 12 (4): 584–592. [CrossRef] [PubMed] [Google Scholar]
  • Schneider JC, El Kebir D, Chéreau C, et al. 2003. Involvement of Ca2+/calmodulin-dependent protein kinase II in endothelial NO production and endothelium-dependent relaxation. Am J Physiol Heart Circ Physiol 284 (6): H2311– H2319. [CrossRef] [PubMed] [Google Scholar]
  • Schurr A, Rigor BM. 1998. Brain anaerobic lactate production: a suicide note or a survival kit? J Dev Neurosci 20 (4-5): 348–357. [CrossRef] [PubMed] [Google Scholar]
  • Selva DM, Hammond GL. 2009. Peroxisome-proliferator receptor gamma represses hepatic sex hormone-binding globulin expression. Endocrinology 150 (5): 2183–2189. [CrossRef] [PubMed] [Google Scholar]
  • Shah RC, Sanker S, Wood KC, Durgin BG, Straub AC. 2018. Redox regulation of soluble guanylyl cyclase. Nitric Oxide 76: 97–104. [CrossRef] [PubMed] [Google Scholar]
  • Shi J, Simpkins JW. 1997. 17 beta-Estradiol modulation of glucose transporter 1 expression in blood-brain barrier. Am J Physiol 272(6 Pt 1): E1016– E1022. [Google Scholar]
  • Shingo AS, Kito S. 2003. Estrogen induces insulin-like growth factor-1 mRNA expression in the immortalized hippocampal cell: determination by quantitative real-time polymerase chain reaction. Neurochem Res 28 (9): 1379–1383. [CrossRef] [PubMed] [Google Scholar]
  • Simpson ER, Misso M, Hewitt KN, et al. 2005. Estrogen-the good, the bad, and the unexpected. Endocr Rev 26: 322–330. [CrossRef] [PubMed] [Google Scholar]
  • Simpson IA, Dwyer D, Malide D, Moley KH, Travis A, Vannucci SJ. 2008. The facilitative glucose transporter GLU T3: 20 years of distinction. Am J Physiol Endocrinol Metab 295 (2): E242– E253. [CrossRef] [PubMed] [Google Scholar]
  • Sinclair AJ, Crawford MA. 1972. The incorporation of linolenic and docosahexaenoic acid into liver and brain lipids of developing rats. FEBS Lett 26: 127–129. [CrossRef] [PubMed] [Google Scholar]
  • Smith CD, Carney JM, Starke-Reed PE, et al. 1991. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Nat Acad Sci U S A 88 (23): 10540–10543. [CrossRef] [PubMed] [Google Scholar]
  • Södergard R, Bäckström T, Shanbhag V, Carstensen H xx 1; 1982. [Google Scholar]
  • Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature. J. Steroid Biochem 16 (6):xxxx 801–810. [Google Scholar]
  • Song RX, Barnes CJ, Zhang Z, Bao, Y, Kumar R, Santen RJ. 2004. The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane. Proc Natl Acad Sci USA 101 (7): 2076–2081. [CrossRef] [PubMed] [Google Scholar]
  • Song RX, Chen Y, Zhang Z, et al. 2010. Estrogen utilization of IGF-1-R and EGF-R to signal in breast cancer cells. J Steroid Biochem Mol Biol 118 (4-5): 219–230. [CrossRef] [PubMed] [Google Scholar]
  • Song J, Li C, Lv Y, Zhang Y, Amakye WK, Mao L. 2017. DHA increases adiponectin expression more effectively than EPA at relative low concentrations by regulating PPARγ and its phosphorylation at Ser273 in 3T3-L1 adipocytes. Nutr Metab (Lond) 14: 52. [CrossRef] [PubMed] [Google Scholar]
  • Srivastava RA, Bhasin N, Srivastava N. 1996. Apolipoprotein E gene expression in various tissues of mouse and regulation by estrogen. Biochem Mol Biol Int 38 (1): 91–101. [PubMed] [Google Scholar]
  • Srivastava RA, Srivastava N, Averna M, et al. 1997. Estrogen up-regulates apolipoprotein E (ApoE) gene expression by increasing ApoE mRNA in the translating pool via the estrogen receptor alpha-mediated pathway. J Biol Chem 272 (52): 33360–33366. [CrossRef] [PubMed] [Google Scholar]
  • Stebbins CL, Stice JP, Hart CM, Mbai FN, Knowlton AA. 2008. Effects of dietary decosahexaenoic acid (DHA) on eNOS in human coronary artery endothelial cells. J Cardiovasc Pharmacol Ther 13 (4): 261–268. [CrossRef] [PubMed] [Google Scholar]
  • Stirone C, Boroujerdi A, Duckles SP, Krause DN. 2005. Estrogen receptor activation of phosphoinositide-3 kinase, akt, and nitric oxide signaling in cerebral blood vessels: rapid and long-term effects. Mol Pharmacol 67 (1): 105–113. [CrossRef] [PubMed] [Google Scholar]
  • Stobart JL, Lu L, Anderson HD, Mori H, Anderson CM. 2013. Astrocyte-induced cortical vasodilation is mediated by D-serine and endothelial nitric oxide synthase. Proc Natl Acad Sci USA 110 (8): 3149–3154. [CrossRef] [PubMed] [Google Scholar]
  • Stocco DM. 2001. StAR protein and the regulation of steroid hormone biosynthesis. Annu Rev Physiol 63: 193–213. [CrossRef] [PubMed] [Google Scholar]
  • Stoffel W, Holz B, Jenke B, et al. 2008. Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids. EMBO J 27 (17): 2281–2292. [CrossRef] [PubMed] [Google Scholar]
  • Stone DJ, Rozovsky I, Morgan TE, Anderson CP, Hajian H, Finch CE. 1997. Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro. Exp Neurol 143 (2): 313–318. [CrossRef] [PubMed] [Google Scholar]
  • Struble RG, Rosario ER, Kircher ML, et al. 2003. Regionally specific modulation of brain apolipoprotein E in the mouse during the estrous cycle and by exogenous 17beta estradiol. Exp Neurol 183 (2): 638–644. [CrossRef] [PubMed] [Google Scholar]
  • Sun C, Zou M, Wang X, et al. 2018. FADS1-FADS2 and ELOVL2 gene polymorphisms in susceptibility to autism spectrum disorders in Chinese children. BMC Psychiatry 18 (1): 283. [CrossRef] [PubMed] [Google Scholar]
  • Szablewski L. 2017. Glucose transporters in brain: in health and in Alzheimer’s disease. J Alzheimers Dis 55 (4): 1307–1320. [Google Scholar]
  • Tan XL, Xue YQ, Ma T, et al. 2015. Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment. Mol Neurodegener 10: 24. [CrossRef] [PubMed] [Google Scholar]
  • Tang C, Cho HP, Nakalura MT, Clarke SD. 2003. Regulation of human delta-6 desaturase gene transcription: identification of a functional direct repeat-1 element. J Lipid Res 44 (4): 686–695. [CrossRef] [PubMed] [Google Scholar]
  • Thies F, Pillon C, Moliere P, Lagarde M, Lecerf J. 1994. Preferential incorporation of sn-2 lysoPC DHA over unesterified DHA in the young rat brain. Am J Physiol 267(5 Pt 2): R1273– R1279. [PubMed] [Google Scholar]
  • Thorns V, Hansen L, Masliah E. 1998. nNOS expressing neurons in the entorhinal cortex and hippocampus are affected in patients with Alzheimer’s disease. Exp Neurol 150 (1): 14–20. [CrossRef] [PubMed] [Google Scholar]
  • Tosi F, Sartori F, Guarini P, Olivieri O, Martinelli N. 2014. Delta-5 and delta-6 desaturases: crucial enzymes in polyunsaturated fatty acid-related pathways with pleiotropic influences in health and disease. Adv Exp Med Biol 824: 61–81. [CrossRef] [PubMed] [Google Scholar]
  • Treebak JT, Glund S, Deshmukh A, et al. 2006. AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits. Diabetes 55 (7): 2051–2058. [CrossRef] [PubMed] [Google Scholar]
  • Tsukada H., Kakiuchi T, Fukumoto D, Nishiyama S, Koga K. 2000. Docosahexaenoic acid (DHA) improves the age-related impairment of the coupling mechanism between neuronal activation and functional cerebral blood flow response: a PET study in conscious monkeys. Brain Res 862 (1-2): 180–186. [CrossRef] [PubMed] [Google Scholar]
  • de Urquiza AM, Liu S, Sjöberg M, et al. 2000. Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science 290 (5499): 2140–2144. [CrossRef] [PubMed] [Google Scholar]
  • Ulatowski L, Ghelfi M, West R, Atkinson J, Finno CJ, Manor D. 2022. The tocopherol transfer protein mediates vitamin E trafficking between cerebellar astrocytes and neurons. J Biol Chem 298 (3): 101712. [CrossRef] [PubMed] [Google Scholar]
  • Varea O, Arevalo MA, Garrido JJ, Garcia-Segura LM, Wandosell F, Mendez P. 2010. Interaction of estrogen receptors with insulin-like growth factor-I and Wnt signaling in the nervous system. Steroids 75 (8-9): 565–569. [CrossRef] [PubMed] [Google Scholar]
  • Vázquez-Chantada M, Ariz U, Varela-Rey M, et al. 2009. Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation. Hepatology 49 (2): 608–617. [CrossRef] [PubMed] [Google Scholar]
  • Verleysdonk S, Hirschner W, Wellard J, et al. 2004. Regulation by insulin and insulin-like growth factor of 2-deoxyglucose uptake in primary ependymal cell cultures. Neurochem Res 29 (1): 127–134. [CrossRef] [PubMed] [Google Scholar]
  • Vindis C, Cerretti DP, Daniel TO, Huynh-Do U. 2003. EphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis. J Cell Biol 62 (4): 661–671. [CrossRef] [PubMed] [Google Scholar]
  • Voss A, Reinhart M, Sankarappa S, Sprecher H. 1991. The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase. J Biol Chem 266 (30): 19995–20000. [PubMed] [Google Scholar]
  • Wang DY, Fulthorpe R, Liss SN, Edwards EA. 2004. Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EE IG1. Mol Endocrinol 18 (2): 402–411. [CrossRef] [PubMed] [Google Scholar]
  • Wang JM, Irwin RW, Brinton RD. 2006. Activation of estrogen receptor alpha increases and estrogen receptor beta decreases apolipoprotein E expression in hippocampus in vitro and in vivo. Proc Natl Acad Sci U S A 103 (45): 16983–16988. [CrossRef] [PubMed] [Google Scholar]
  • Wang H, Chen F, Zhong KL, et al. 2016. PPARγ agonists regulate bidirectional transport of amyloid-β across the blood-brain barrier and hippocampus plasticity in db/db mice. Br J Pharmacol 173 (2): 372–385. [CrossRef] [PubMed] [Google Scholar]
  • Wary KK., Mariotti A, Zurzolo C, Giancotti FG. 1998. A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell 94 (5): 625–634. [CrossRef] [PubMed] [Google Scholar]
  • Weiner CP, Lizasoain I, Baylis SA, Knowles RG, Charles IG, Moncada S. 1994. Induction of calcium-dependent nitric oxide synthases by sex hormones. Proc Natl Acad Sci 91 (11): 5212–5216. [CrossRef] [PubMed] [Google Scholar]
  • Weisová P, Concannon CG, Devocelle M, Prehn JH, Ward MW. 2009. Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons. J Neurosci 29 (9): 2997–3008. [CrossRef] [PubMed] [Google Scholar]
  • Widnell CC. 1995. Control of glucose transport by GLU T1: Regulated secretion in an unexpected environment. Biosci Rep 15 (6): 427–443. [CrossRef] [PubMed] [Google Scholar]
  • Wieman HL, Horn SR, Jacobs SR, Altman BJ, Kornbluth S, Rathmell JC. 2009. An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking. Biochem J 418 (2): 345–367. [CrossRef] [PubMed] [Google Scholar]
  • Wiencken AE, Casagrande VA. 1999. Endothelial nitric oxide synthetase (eNOS) in astrocytes: another source of nitric oxide in neocortex. Glia 1999. 26 (4): 280–290. [Google Scholar]
  • Wilson MC, Meredith D, Fox JE, Manoharan C, Davies AJ, Halestrap AP. 2005. Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70). J Biol Chem 280 (29): 27213–27221. [CrossRef] [PubMed] [Google Scholar]
  • Yu Z, Gao W, Jiang E, et al. 2013. Interaction between IGF-IR and ER induced by E2 and IGF-I. PLoS One 8 (5): e62642. [CrossRef] [PubMed] [Google Scholar]
  • Zheng WH, Kar S, Dore S, Quirion R. 2000. Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway. J Neural Transm Suppl 60: 261–272. [Google Scholar]
  • Zonta M, Angulo MC, Gobbo S, et al. 2003. Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation. Nat Neurosci 6 (1): 43–50. [CrossRef] [PubMed] [Google Scholar]
  • Zwain IH, Yen SS. 1999. Neurosteroidogenesis in astrocytes, oligodendrocytes, and neurons of cerebral cortex of rat brain. Endocrinology 140 (8): 3843–3852. [CrossRef] [PubMed] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.