Volume 28, 2021
Microbiota, Nutrition and Lipids: consequences on Health
Article Number 21
Number of page(s) 7
Published online 22 March 2021
  • Afshin A, Forouzanfar MH, Reitsma MB, et al. 2017. Health Effects of Overweight and Obesity in 195 Countries over 25 Years. N Engl J Med 377(1): 13–27. [Google Scholar]
  • Andersen AD, Molbak L, Michaelsen KF, Lauritzen L. 2011. Molecular fingerprints of the human fecal microbiota from 9 to 18 months old and the effect of fish oil supplementation. J Pediatr Gastroenterol Nutr 53(3): 303–309. [PubMed] [Google Scholar]
  • Aung T, Halsey J, Kromhout D, et al. 2018. Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks: Meta-analysis of 10 Trials Involving 77917 Individuals. JAMA Cardiol 3(3): 225–234. [PubMed] [Google Scholar]
  • Backhed F, Ding H, Wang T, et al. 2004. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA 101(44): 15718–15723. [Google Scholar]
  • Bidu C, Escoula Q, Bellenger S, et al. 2018. The Transplantation of omega3 PUFA-Altered Gut Microbiota of fat-1 Mice to Wild-Type Littermates Prevents Obesity and Associated Metabolic Disorders. Diabetes 67(8): 1512–1523. [PubMed] [Google Scholar]
  • Brignardello J, Morales P, Diaz E, Romero J, Brunser O, Gotteland M. 2010. Pilot study: alterations of intestinal microbiota in obese humans are not associated with colonic inflammation or disturbances of barrier function. Aliment Pharmacol Ther 32(11-12): 1307–1314. [Google Scholar]
  • Cani PD, Amar J, Iglesias MA, et al. 2007. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 56(7): 1761–1772. [CrossRef] [PubMed] [Google Scholar]
  • Cani PD, Bibiloni R, Knauf C, et al. 2008. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57(6): 1470–1481. [CrossRef] [PubMed] [Google Scholar]
  • Chavez JA, Knotts TA, Wang LP, et al. 2003. A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J Biol Chem 278(12): 10297–10303. [CrossRef] [PubMed] [Google Scholar]
  • Chelakkot C, Ghim J, Ryu SH. 2018. Mechanisms regulating intestinal barrier integrity and its pathological implications. Exp Mol Med 50(8): 103. [Google Scholar]
  • Davidson MH. 2006. Mechanisms for the hypotriglyceridemic effect of marine omega-3 fatty acids. Am J Cardiol 98(4a): 27i–33i. [PubMed] [Google Scholar]
  • Davis JE, Gabler NK, Walker-Daniels J, Spurlock ME. 2008. Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat. Obesity (Silver Spring) 16(6): 1248–1255. [Google Scholar]
  • Echeverría F, Valenzuela R, Espinosa A, et al. 2019. Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: involvement of resolvins RvE1/2 and RvD1/2. J Nutr Biochem 63: 35–43. [Google Scholar]
  • Escoula Q, Bellenger S, Narce M, Bellenger J. 2019. Docosahexaenoic and Eicosapentaenoic Acids Prevent Altered-Muc2 Secretion Induced by Palmitic Acid by Alleviating Endoplasmic Reticulum Stress in LS174T Goblet Cells. Nutrients 11(9): 2179. [Google Scholar]
  • Everard A, Belzer C, Geurts L, et al. 2013. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci USA 110(22): 9066–9071. [CrossRef] [Google Scholar]
  • Feral-Pierssens AL, Carette C, Rives-Lange C, et al. 2018. Obesity and emergency care in the French CONSTANCES cohort. PLoS One 13(3): e0194831. [Google Scholar]
  • Gérard P. 2016. Gut microbiota and obesity. Cell Mol Life Sci 73(1): 147–162. [CrossRef] [PubMed] [Google Scholar]
  • Guha P, Kaptan E, Gade P, Kalvakolanu DV, Ahmed H. 2017. Tunicamycin induced endoplasmic reticulum stress promotes apoptosis of prostate cancer cells by activating mTORC1. Oncotarget 8: 68191–68207. [PubMed] [Google Scholar]
  • Gulhane M, Murray L, Lourie R, et al. 2016. High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22. Sci Rep 6: 28990. [PubMed] [Google Scholar]
  • Jiang WG, Bryce RP, Horrobin DF, Mansel RE. 1998. Regulation of tight junction permeability and occludin expression by polyunsaturated fatty acids. Biochem Biophys Res Commun 244(2): 414–420. [Google Scholar]
  • Johnson AM, Costanzo A, Gareau MG, et al. 2015. High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. PLoS One 10(4): e0122195. [Google Scholar]
  • Jung TW, Hwang HJ, Hong HC, et al. 2014. Resolvin D1 reduces ER stress-induced apoptosis and triglyceride accumulation through JNK pathway in HepG2 cells. Mol Cell Endocrinol 391(1-2): 30–40. [PubMed] [Google Scholar]
  • Kaliannan K, Wang B, Li XY, Kim KJ, Kang JX. 2015. A host-microbiome interaction mediates the opposing effects of omega-6 and omega-3 fatty acids on metabolic endotoxemia. Sci Rep 5: 11276. [PubMed] [Google Scholar]
  • Katsoulieris E, Mabley JG, Samai M, Green IC, Chatterjee PK. 2009. Alpha-Linolenic acid protects renal cells against palmitic acid lipotoxicity via inhibition of endoplasmic reticulum stress. Eur J Pharmacol 623(1-3): 107–112. [PubMed] [Google Scholar]
  • Kim EH, Bae JS, Hahm KB, Cha JY. 2012. Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease. Biochem Pharmacol 84(10): 1359–1365. [PubMed] [Google Scholar]
  • Li J, Li FR, Wei D, et al. 2014. Endogenous omega-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice. Mol Endocrinol 28(8): 1316–1328. [Google Scholar]
  • Liu T, Hougen H, Vollmer AC, Hiebert SM. 2012. Gut bacteria profiles of Mus musculus at the phylum and family levels are influenced by saturation of dietary fatty acids. Anaerobe 18(3): 331–337. [PubMed] [Google Scholar]
  • Mani V, Hollis JH, Gabler NK. 2013. Dietary oil composition differentially modulates intestinal endotoxin transport and postprandial endotoxemia. Nutr Metab (Lond) 10(1): 6. [CrossRef] [PubMed] [Google Scholar]
  • Moreira AP, Texeira TF, Ferreira AB, Mdo Peluzio C, Alfenas Rde C. 2012. Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia. Br J Nutr 108(5): 801–809. [CrossRef] [PubMed] [Google Scholar]
  • Pimenta AS, Gaidhu MP, Habib S, et al. 2008. Prolonged exposure to palmitate impairs fatty acid oxidation despite activation of AMP-activated protein kinase in skeletal muscle cells. J Cell Physiol 217(2): 478–485. [Google Scholar]
  • Pinel A, Rigaudiere JP, Laillet B, et al. 2016. N-3PUFA differentially modulate palmitate-induced lipotoxicity through alterations of its metabolism in C2C12 muscle cells. Biochim Biophys Acta 1861(1): 12–20. [CrossRef] [PubMed] [Google Scholar]
  • Płóciennikowska A, Hromada-Judycka A, Borzęcka K, Kwiatkowska K. 2015. Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling. Cell Mol Life Sci 72(3): 557–581. [PubMed] [Google Scholar]
  • Plovier H, Everard A, Druart C, et al. 2017. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nat Med 23(1): 107–113. [CrossRef] [PubMed] [Google Scholar]
  • Saad MJ, Santos A, Prada PO. 2016. Linking Gut Microbiota and Inflammation to Obesity and Insulin Resistance. Physiology (Bethesda) 31(4): 283–293. [PubMed] [Google Scholar]
  • Teixeira TF, Souza NC, Chiarello PG, et al. 2012. Intestinal permeability parameters in obese patients are correlated with metabolic syndrome risk factors. Clin Nutr 31(5): 735–740. [CrossRef] [PubMed] [Google Scholar]
  • Thaiss CA, Levy M, Grosheva I, et al. 2018. Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection. Science 359(6382): 1376–1383. [Google Scholar]
  • Turnbaugh PJ, Backhed F, Fulton L, Gordon JI. 2008. Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 3(4): 213–223. [CrossRef] [PubMed] [Google Scholar]
  • Vieira-Silva S, Falony G, Belda E, et al. 2020. Statin therapy is associated with lower prevalence of gut microbiota dysbiosis. Nature 581(7808): 310–315. [PubMed] [Google Scholar]
  • White PJ, Marette A. 2014. Potential role of omega-3-derived resolution mediators in metabolic inflammation. Immunol Cell Biol 92(4): 324–330. [PubMed] [Google Scholar]
  • White PJ, Arita M, Taguchi R, Kang JX, Marette A. 2010. Transgenic restoration of long-chain n-3 fatty acids in insulin target tissues improves resolution capacity and alleviates obesity-linked inflammation and insulin resistance in high-fat-fed mice. Diabetes 59: 3066–3073. [PubMed] [Google Scholar]
  • Yang W, Chen X, Chen M, et al. 2017. Fish oil supplementation inhibits endoplasmic reticulum stress and improves insulin resistance: involvement of AMP-activated protein kinase. Food Funct 8(4): 1481–1493. [Google Scholar]
  • Yu HN, Zhu J, Pan WS, et al. 2014. Effects of fish oil with a high content of n-3 polyunsaturated fatty acids on mouse gut microbiota. Arch Med Res 45(3): 195–202. [PubMed] [Google Scholar]
  • Zhang Y, Dong L, Yang X, Shi H, Zhang L. 2011. alpha-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes. Lipids Health Dis 10: 81. [PubMed] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.