Table 2

Harm severity index and occupational safety score

Criteria Hexane Iso-Hx Cyc Hex MeOH EtOH IPA Acetone MEK EA DCM 2-MeOx
Occupational safety 1 3 3 2 4 5 5 5 5 1 2
Acute Tox. 3 H301 0 0 0 5 0 0 0 0 0 0 0
Acute Tox. 4 H302 0 0 0 0 1 0 0 0 0 1 1
Asp. Tox. 1 H304 10 10 10 0 0 0 0 0 0 0 0
Acute Tox. 3 H311 0 0 0 1 0 0 0 0 0 0 0
Skin Irritant 2 H315 1 1 1 0 1 0 0 0 0 1 1
Eye dam. 1 H318 0 0 0 0 0 0 0 0 0 0 5
Eye Irritant 2 H319 1 1 0 0 1 1 1 1 1 1
Acute Tox. 3 H331 0 0 0 1 0 0 0 0 0 0 0
STOT SE 3 H336 1 1 1 0 0 1 1 1 1 1 1
Mutagen 2 H341 0 0 0 0 0 0 0 0 0 5 0
Carcinogen. 2 H351 0 0 0 5 0 0 0 0 0 10 0
Reprotoxic 2 H361f 5 0 0 0 0 0 0 0 0 0 0
STOT SE 1 H370 0 0 0 5 3 0 0 0 0 0 0
STOT SE 2 H371 0 0 0 0 0 1 0 0 0 0
STOT RE 1 H372 5 0 0 0 0 0 0 0 0 0 0
STOT RE 2 H373 0 0 0 0 0 0 0 0 1 0
Severity index 23 13 12 17 6 2 3 2 2 20 8

Abbreviations meaning: Acute Tox. 3/4: Acute Toxicity Category 3/4; Asp. Tox. 1: Aspiration Toxicity Category 1; H311: Toxic in contact with skin; Skin Irritant 2: Skin Irritation Category 2; Eye Dam. 1: Serious Eye Damage Category 1; Eye Irritant 2: Eye Irritation Category 2; STOT SE 1: Specific Target Organ Toxicity – Single Exposure Category 1; STOT SE 2: Specific Target Organ Toxicity – Single Exposure Category 2; STOT SE 3: Specific Target Organ Toxicity – Single Exposure Category 3; STOT RE 1: Specific Target Organ Toxicity – Repeated Exposure Category 1; STOT RE 2: Specific Target Organ Toxicity – Repeated Exposure Category 2; Mutagen 2: Germ Cell Mutagenicity Category 2; Carcinogen. 2: Carcinogenicity Category 2; Reprotoxic 2: Reproductive Toxicity Category 2. The categories generally indicate the severity of the hazard, with lower numbers typically representing more severe effects.

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