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Table 2.
Expression of genes involved in DHA biosynthesis and peroxisomal function in liver of control subjects and subjects with AD.
| Gene | Control Subjects | Subjects with AD | P-value |
|---|---|---|---|
| Symbol | Mean±SD; N = 9 | Mean±SD; N=14 | |
| FADS2 | 0.02±0.029 | 0.016±0.0099 | 0.851 |
| HELO1 | 0.011±0.012 | 0.006±0.0046 | 0.265 |
| FADS1 | 0.037±0.061 | 0.024±0.026 | 0.693 |
| ABCD1 | 0.027±0.034 | 0.02±0.024 | 0.500 |
| ABCD2 | 8e-04±0.001 | 0.0011±0.0013 | 0.567 |
| ACOX1 | 0.2±0.24 | 0.31±0.68 | 0.782 |
| HSD17B4 | 0.18±0.045 | 0.14±0.046 | 0.048 |
| PEX13 | 0.041±0.017 | 0.037±0.017 | 0.569 |
| PEX14 | 0.0087±0.004 | 0.013±0.022 | 0.700 |
| PEX19 | 0.018±0.018 | 0.012±0.0054 | 0.291 |
Statistical analyses were conducted using a linear regression analysis adjusting for age, gender and RNA integrity number.
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