Volume 18, Number 1, Janvier-Février 2011Dossier : Lipides et inflammation
|Page(s)||11 - 13|
|Section||Nutrition – Santé|
|Published online||15 January 2011|
Lipides et inflammation postprandiale : impact du microbiote intestinal
Louvain Drug Research Institute, LDRI, Université catholique de Louvain, Groupe de Recherche en métabolisme et nutrition Av. E. Mounier, 73/69, B-1200 Bruxelles, Belgique
Obesity and type 2 diabetes are associated with low grade inflammatory tone. Evidence suggest that the gut microbiota could be involved not only in the host metabolism but also in the pathogenesis of the low grade inflammation associated with obesity and type 2 diabetes. Among the mechanisms, dietary habits and more specifically the nutritional composition of the diet (lipids, non digestibles carbohydrates) have been shown to participate to the modulation of the composition and/or the activity of the gut microbiota. These questions and mechanisms will be discussed following experimental data.
Key words: gut microbiota / prebiotics / LPS / CD14 / TLR-4 / obesity / diabetes / inflammation / gut permeability
© John Libbey Eurotext 2011
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