Fig. 1


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Synthesis and degradation of TAG in Y. lipolytica. Colored arrows indicate different metabolic pathways: black: glycolysis; grey: xylose pathway; yellow: oxidative pentose phosphate pathway; red: tricarboxylic acid (TCA) cycle and related intermediate reactions; orange: de novo TAG synthesis pathway; purple: ex novo TAG synthesis pathway; green: Kennedy pathway; blue: β-oxidation pathway. Dashed lines represent multiple metabolic steps. Abbreviations: G6P: glucose-6-phosphate; GAP: glyceraldehyde-3-phosphate; Ru5P: ribulose-5-phosphate; G3P: glycerol-3-phosphate; DHAP: dihydroxyacetone phosphate; LPA: lysophosphatidic acid; PA: phosphatidic acid; DAG: diacylglycerol; TAG: triacylglyceride; FFA: free fatty acid.

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