Table 3
Associations of total n-6, LA levels, n-6/n-3 and LA/ALA ratios in colostrum with child’s psychomotor development at 2 and 3 years among breastfed children of the EDEN study.
| Motor-2 | CDI-2 | ASQ-3 | ||||
| n = 579 | n = 585 | n = 519 | ||||
|
|
||||||
| PUFA, % total fatty acids | β ± SE | P | β ± SE | P | β ± SE | P |
|
|
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| n-6 PUFA, % | –0.10 ± 0.05 | 0.04 | –0.80 ± 0.62 | 0.2 | –1.06 ± 0.55 | 0.05 |
| LA, % | –0.09 ± 0.05 | 0.06 | –0.89 ± 0.64 | 0.2 | –1.05 ± 0.57 | 0.07 |
| Total n-6/n-3 ratio | –0.04 ± 0.06 | 0.5 | –1.24 ± 0.78 | 0.1 | –0.70 ± 0.69 | 0.3 |
| LA/ALA ratio | –0.03 ± 0.02 | 0.10 | –0.15 ± 0.23 | 0.5 | 0.04 ± 0.20 | 0.8 |
Models were adjusted for study centre, day of colostrum collection after delivery, child’s sex and age at assessment, duration of gestation, maternal age, primiparity, maternal pre-pregnancy body mass index, smoking status, alcohol consumption, parental education level, household income, child’s caregiver at 2 years, frequency of mother-child activities, any breastfeeding duration. Models with ASQ were additionally adjusted for duration of preschool attendance at 3 years. SE, standard error; LA, linoleic acid; ALA, alpha-linolenic acid; Motor-2, motor development at 2 years; CDI-2, communicative development inventory at 2 years; ASQ-3, ages and stages questionnaire at 3 years.
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