Associations of total n-6, LA levels, n-6/n-3 and LA/ALA ratios in colostrum with child’s psychomotor development at 2 and 3 years among breastfed children of the EDEN study.
|n = 579||n = 585||n = 519|
|PUFA, % total fatty acids||β ± SE||P||β ± SE||P||β ± SE||P|
|n-6 PUFA, %||–0.10 ± 0.05||0.04||–0.80 ± 0.62||0.2||–1.06 ± 0.55||0.05|
|LA, %||–0.09 ± 0.05||0.06||–0.89 ± 0.64||0.2||–1.05 ± 0.57||0.07|
|Total n-6/n-3 ratio||–0.04 ± 0.06||0.5||–1.24 ± 0.78||0.1||–0.70 ± 0.69||0.3|
|LA/ALA ratio||–0.03 ± 0.02||0.10||–0.15 ± 0.23||0.5||0.04 ± 0.20||0.8|
Models were adjusted for study centre, day of colostrum collection after delivery, child’s sex and age at assessment, duration of gestation, maternal age, primiparity, maternal pre-pregnancy body mass index, smoking status, alcohol consumption, parental education level, household income, child’s caregiver at 2 years, frequency of mother-child activities, any breastfeeding duration. Models with ASQ were additionally adjusted for duration of preschool attendance at 3 years. SE, standard error; LA, linoleic acid; ALA, alpha-linolenic acid; Motor-2, motor development at 2 years; CDI-2, communicative development inventory at 2 years; ASQ-3, ages and stages questionnaire at 3 years.
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