Table 2
Fatty acid composition of cardiac phospholipids.
| Control | HF | ZL | ZDF | |
| SFA | 38.8 ± 0.2 | 43.3 ± 0.9* | 35.9 ± 0.8 | 44.7 ± 1.1* |
| MUFA | 8.9 ± 0.2 | 7.1 ± 0.1* | 9.8 ± 0.4 | 6.2 ± 0.2* |
| PUFA | 52.4 ± 0.1 | 49.8 ± 0.8* | 54.2 ± 0.6 | 49.1 ± 1.2* |
| C18:2 n-6 | 26.5 ± 1.3 | 20.7 ± 1.0* | 32.9 ± 1.8 | 15.7 ± 2.6* |
| C20:4 n-6 | 17.0 ± 0.3 | 19.9 ± 0.8* | 16.0 ± 0.8 | 23.6 ± 1.6* |
| C22:4 n-6 | 0.2 ± 0.1 | 0.5 ± 0.1* | 0.4 ± 0.1 | 0.4 ± 0.1 |
| C22:5 n-6 | 0.2 ± 0.1 | 0.5 ± 0.1* | 0.3 ± 0.1 | 0.4 ± 0.1 |
| n-6 PUFA | 44.4 ± 1.0 | 41.9 ± 0.3* | 50.2 ± 0.9 | 41.2 ± 1.3* |
| C20:5 n-3 | 0.12 ± 0.01 | 0.10 ± 0.02 | 0.10 ± 0.01 | 0.08 ± 0.06 |
| C22:5 n-3 | 0.7 ± 0.1 | 1.8 ± 0.1* | 0.5 ± 0.1 | 1.3 ± 0.1* |
| C22:6 n-3 | 5.5 ± 0.2 | 5.4 ± 0.4 | 3.3 ± 0.4 | 6.5 ± 0.5* |
| n-3 PUFA | 6.4 ± 0.2 | 7.1 ± 0.5 | 4.0 ± 0.5 | 7.9 ± 0.6* |
| n-6/n-3 | 7.0 ± 0.1 | 5.9 ± 0.4 | 13.5 ± 1.7 | 5.4 ± 0.5* |
| EPA/AA | 6.8 ± 0.8 | 5.0 ± 1.1 | 6.1 ± 0.5 | 3.6 ± 0.5* |
| EPA+DHA | 5.7 ± 0.2 | 5.5 ± 0.4 | 3.4 ± 0.4 | 6.6 ± 0.6* |
| C18:0/C16:0 | 1.6 ± 0.1 | 2.5 ± 0.1* | 1.6 ± 0.1 | 1.9 ± 0.1* |
| C18:1n-7/C16:1n-7 | 10.9 ± 1.6 | 22.0 ± 3.0* | 10.4 ± 0.5 | 9.4 ± 0.5 |
| C20:2n-6/C18:2n-6 | 3.9 ± 0.1 | 10.3 ± 0.7* | 5.3 ± 0.7 | 12.8 ± 3.2* |
| C22:4n-6/C20:4n-6 | 1.4 ± 0.1 | 2.4 ± 0.1* | 2.4 ± 0.1 | 1.6 ± 0.1* |
| C22:5n-3/C20:5n-3 | 7.2 ± 1.7 | 25.4 ± 5.6* | 5.1 ± 0.4 | 15.6 ± 1.6* |
| C16:1n-7/C16:0 | 4.0 ± 0.6 | 1.2 ± 0.1* | 4.4 ± 0.1 | 2.7 ± 0.1* |
| C18:3n-6/C18:2n-6 | 7.8 ± 0.5 | 3.7 ± 0.8 * | – | – |
| C20:4n-6/C20:3n-6 | 62.7 ± 5.6 | 33.4 ± 2.7* | 41.6 ± 4.1 | 25.2 ± 4.7* |
The number of experiments was 10 per group. The EPA to AA ratio must be multiplied by 10-3. The C22:4 n-6/20:4 n-6 and C16:1 n-7/C16:0 ratios must be multiplied by 10-2. The C20:2 n-6/C18:2 n-6 and C18:3 n-6/C18:2 n-6 ratios must be multiplied by 10-3 and 10-4, respectively. HF: high fat fed rats; ZL: Zucker lean rats; ZDF: Zucker Diabetic Fatty rats; SFA: sum of saturated fatty acids; MUFA sum of monounsaturated fatty acids; PUFA: sum of polyunsaturated fatty acids; n-6/n-3: n-6/n-3 PUFA ratio; EPA: eicosapentaenoic acid or C20:5 n-3, AA: arachidonic acid or C20:4 n-6; DHA: docosahexaeboic acid or C22:6 n-3; -: missing data; *: significantly different between HF and control rats or ZL and ZDF animals.
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