Table 1.
Associations between plasma EPA and DHA proportions and 4-y incident dementia in the Bordeaux sample of the Three-City study (N=1,214), 1999-2004, published in (Samieri et al, 2008)
| Risk of dementia | ||||||
|---|---|---|---|---|---|---|
| Model 11 | Model 22 | |||||
| Plasma fatty acids | HR | 95% CI | P | HR | 95% CI | P |
| EPA | ||||||
| for 1 SD of plasma proportion | 0.69 | 0.48, 0.98 | 0.04 | 0.69 | 0.48, 0.98 | 0.04 |
| Depressive status | - | - | - | 2.16 | 1.08, 4.34 | 0.03 |
| DHA | ||||||
| for 1 SD of plasma proportion | 0.84 | 0.63, 1.11 | 0.21 | 0.83 | 0.62, 1.10 | 0.19 |
| Depressive status | - | - | - | 2.22 | 1.10, 4.46 | 0.03 |
Cox proportional hazard models with delayed entry taking age as a time scale and adjusted for education (in four levels), ApoE4 allele, diabetes, plasma triacylglycerides, plasma vitamin E.
Abbreviations: EPA: eicosapentaenoic acid; DHA: docosahexaenoic acid; HR: Hazard Ratio; SD: Standard Deviation.
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