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Table 5.

Mechanisms of omega-6/omega-3 fatty acids.

Linoleic acid inhibits eicosapentaenoic acid incorporation from dietary fish oil supplements in human subjects
Linoleic acid increases low-density lipoprotein oxidation and severity of coronary atherosclerosis
As the omega-6/omega-3 ratio decreases, so does the platelet aggregation
Plasma omega-6/omega-3 ratio and inflammatory markers (the omega-6/omega-3 ratio is a strong negative correlate of IL-10)
Omega-3 fatty acids downregulate the expression of genes involved in inflammation and obesity
A Lower omega-6/omega-3 ratio as part of a mediterranean diet decreases vascular endothelial growth factor
Decreasing linoleic acid with constant α-linolenic acid in dietary fat increases eicosapentaenoic acid in plasma phospholipids in healthy men

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