Open Access
Table 4.
Effects of ingestion of EPA and DHA from fish or fish oil.
| Decreased production of prostaglandin E2 (PGE2) metabolites |
| A decrease in thromboxane A2, a potent platelet aggregator and vasoconstrictor |
| A decrease in leukotriene B4 formation, an inducer of inflammation, and a powerful inducer of leukocyte chemotaxis and adherence |
| An increase in thromboxane A3, a weak platelet aggregator and weak vasoconstrictor |
| An increase in prostacyclin PGI3, leading to an overall increase in total prostacyclin by increasing PGI3 without a decrease in PGI2, both PGI2 and PGI3 are active vasodilators and inhibitors of platelet aggregation |
| An increase in leukotriene B5, a weak inducer of inflammation and a weak chemotactic agent |
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