Effects of ingestion of EPA and DHA from fish or fish oil.
|Decreased production of prostaglandin E2 (PGE2) metabolites|
|A decrease in thromboxane A2, a potent platelet aggregator and vasoconstrictor|
|A decrease in leukotriene B4 formation, an inducer of inflammation, and a powerful inducer of leukocyte chemotaxis and adherence|
|An increase in thromboxane A3, a weak platelet aggregator and weak vasoconstrictor|
|An increase in prostacyclin PGI3, leading to an overall increase in total prostacyclin by increasing PGI3 without a decrease in PGI2, both PGI2 and PGI3 are active vasodilators and inhibitors of platelet aggregation|
|An increase in leukotriene B5, a weak inducer of inflammation and a weak chemotactic agent|
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