Issue |
OCL
Volume 12, Number 1, Janvier-Février 2005
|
|
---|---|---|
Page(s) | 18 - 21 | |
Section | Dossier | |
DOI | https://doi.org/10.1051/ocl.2005.0018 | |
Published online | 15 January 2005 |
CLAs, nature, origin and some metabolic aspects
1
Inra, Unité de nutrition lipidique, 17, rue Sully, BP 86510, 21065
Dijon Cedex
2
Inra-Université d’Auvergne, Unité du métabolisme protéino-énergétique, Clermont-Ferrand
CLA (conjugated linoleic acid) is a generic term for several isomers of linoleic acid with conjugated double bonds. They have been reported since 1935 in butter fat, but the major natural isomer (9cis,11trans-18 :2) was identified in 1977 and further named « rumenic acid ». This fatty acid is formed in the rumen as a product of biohydrogenation. Tissues may also produce rumenic acid from vaccenic acid, which is a further intermediate of ruminal biohydrogenation. Interest for CLAs started with a report on beneficial effects of CLA from grilled beef on skin tumours. CLA was produced as mixtures of isomers from chemically modified vegetable oil. As a metabolic point of view, it has been shown that rumenic acid is bioconverted like linoleic acid and beta-oxidised. CLA isomers may also interfere with the metabolism of other fatty acids. Other targets than skin tumours have also been identified. These aspects will be developed in other sections of the present issue.
Key words: CLA / rumen / milk / meat / metabolism
© John Libbey Eurotext 2005
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.