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Fatty taste variability in obese subjects: the oral microbiota hypothesis. A. Schematic structure of circumvallate papillae. B. Simplified LCFA-mediated signaling in taste bud cells (modified from (Besnard et al., 2016)). HLT: High-lipid taster; LCFA: Long-chain fatty acid; ER: Endoplasmic reticulum; DRK: Delayed rectifying K+ channel; PIP2: Phosphatidyl-inisitol diphosphate.
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