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Simplified overview of the pathways of eicosanoid synthesis from ARA. ARA: arachidonic acid; COX: cyclooxygenase; CYT P450: cytochrome P450 enzymes; EET: epoxyeicosatrienoic acid; HETE: hydroxyeicosatetraenoic acid; LOX: lipoxygenase; LT: leukotriene; PLA2: phospholipase A2; PG: prostaglandin; TX: thromboxane. Reprinted with modifications from Innes and Calder (2018) with permission from Elsevier.
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