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Table 1

Key points linking medium chain fatty acids, ketones and normal infant brain development.

Ketones supply > 30% of late brain and about 50% (Adam et al., 1975)
of neonatal brain energy needs (Bougneres et al., 1986)

Medium chain fatty acids are present at 10–15% of maternal (Sarda et al., 1987)
milk fatty acids and 8–10% of neonatal body fat

Ketones supply 90% of the carbon to make (Cunnane et al., 2003)
brain cholesterol, saturated fats

Octanoic acid is rapidly taken up and metabolized by the brain (Kuge et al., 1995),
(Ebert et al., 2003)

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