Volume 12, Number 4, Juillet-Août 2005
|Page(s)||299 - 301|
|Published online||15 July 2005|
Paramètres de solubilité
Clef du succès en formulation !
RHODIA Recherches & Technologies Centre de Recherches et Technologies d’Aubervilliers (CRTA), Pôle Formulation et Revêtement. Laboratoire Applicabilité 52, rue de la Haie coq
F - 93308
33 (0) 1 49 37 63 02
The Hansen solubility parameter method, whilst undoubtedly an important advance academically was, in practice, little used. However this method can save considerable time in developing formulations in many different kinds of industrial activities.
The way of formulating an active chemical is often difficult. Is it better to choose an aqueous or non aqueous solution, with one solvent or several? Is an emulsion preferable? What to do to formulate several solutes in the same system?
The main principles are established before studying the applications: how to choose a single solvent or a solvent blend, how to “create” a new solvent with well defined properties, the choice of an oil to make an emulsion or how to formulate several solutes in a single formulation. Then the limits of the method are explored.
Key words: emulsion / formulation / Hansen / Hildebrand / solubility / volume
© John Libbey Eurotext 2005
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